Literature DB >> 25934120

How do base-pairing small RNAs evolve?

Taylor B Updegrove1, Svetlana A Shabalina2, Gisela Storz3.   

Abstract

The increasing numbers of characterized base-pairing small RNAs (sRNAs) and the identification of these regulators in a broad range of bacteria are allowing comparisons between species and explorations of sRNA evolution. In this review, we describe some examples of trans-encoded base-pairing sRNAs that are species-specific and others that are more broadly distributed. We also describe examples of sRNA orthologs where different features are conserved. These examples provide the background for a discussion of mechanisms of sRNA evolution and selective pressures on the sRNAs and their mRNA target(s). Published by Oxford University Press on behalf of FEMS 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

Keywords:  Hfq; evolution; mosaic pattern of selective pressure; sRNAs

Mesh:

Substances:

Year:  2015        PMID: 25934120      PMCID: PMC4542690          DOI: 10.1093/femsre/fuv014

Source DB:  PubMed          Journal:  FEMS Microbiol Rev        ISSN: 0168-6445            Impact factor:   16.408


  111 in total

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