Literature DB >> 25932433

Paralysis developing as a paradoxical response during treatment for tuberculous spondylitis.

Safak Ekinci1, Faruk Akyildiz2, Yavuz Poyrazoglu3, Samet Verim4.   

Abstract

Entities:  

Year:  2015        PMID: 25932433      PMCID: PMC4414983          DOI: 10.5535/arm.2015.39.2.327

Source DB:  PubMed          Journal:  Ann Rehabil Med        ISSN: 2234-0645


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Dear Editor We read with great interest the published article by Park et al. [1] entitled "Paralysis Developing as a Paradoxical Response During the Treatment for Tuberculous Spondylitis: A Case Report". The authors report the case of a 69-year-old woman who experienced bilateral lower extremity paralysis secondary to a paradoxical response. We think several more points should be discussed concerning therapy. Spinal tuberculosis is the most common and the worst form of tuberculosis lesions in the skeleton [2,3,4]. If the lesion is limited to the vertebrae and there are no complications, triple-drug anti-tuberculous chemotherapy can be the main therapy to treat tuberculosis [5]. However, with proper indications, surgical procedures are superior in the prevention of neurological deterioration, maintenance of stability and early recovery [3,4,5,6]. Oguz et al. [4] reported on 76 cases with spinal tuberculosis between 1989 to 2002 without any neurological deterioration that all featured eventual excellent recovery. As a result, these authors developed a effective classification system abbreviated GATA (Gulhane Askeri Tip Akademisi). This new classification system has been using as a practical guide in the treatment of Pott disease. In the case that was presented in the article, despite the initiation of medical treatment, deterioration in the clinical status of the patient was observed. However, when we examined the MRI in Fig. 1, we noted vertebral collapse and abcess formation, which is type II in the GATA classification system. Type II treatment is anterior debridement and fusion. As a result, we believe that if surgical intervention is made at the time of diagnosis (early stage), the patient will heal more quickly without any neurological deterioration.
  6 in total

1.  A new classification and guide for surgical treatment of spinal tuberculosis.

Authors:  E Oguz; A Sehirlioglu; M Altinmakas; C Ozturk; M Komurcu; C Solakoglu; A R Vaccaro
Journal:  Int Orthop       Date:  2007-01-06       Impact factor: 3.075

Review 2.  [Role of surgery in the treatment of Pott's disease in adults. Apropos of 29 cases].

Authors:  M Ghadouane; O Elmansari; N Bousalmame; K Lezrek; H Aouam; I Moulay
Journal:  Rev Chir Orthop Reparatrice Appar Mot       Date:  1996

3.  Conservative treatment of tuberculosis of the lumbar and lumbosacral spine.

Authors:  Myung-Sang Moon; Young-Wan Moon; Jeong-Lim Moon; Sung-Sim Kim; Doo-Hoon Sun
Journal:  Clin Orthop Relat Res       Date:  2002-05       Impact factor: 4.176

4.  Modern management of spinal tuberculosis.

Authors:  A R Rezai; M Lee; P R Cooper; T J Errico; M Koslow
Journal:  Neurosurgery       Date:  1995-01       Impact factor: 4.654

Review 5.  Tuberculosis of the spine.

Authors:  O Boachie-Adjei; R G Squillante
Journal:  Orthop Clin North Am       Date:  1996-01       Impact factor: 2.472

6.  Paralysis developing as a paradoxical response during the treatment for tuberculous spondylitis: a case report.

Authors:  Jae Hyeon Park; Yeo Hyung Kim; Chan Hyuk Kwon; Hyung-Ik Shin
Journal:  Ann Rehabil Med       Date:  2014-06-26
  6 in total

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