Literature DB >> 25931880

A rare cause of acute mesenteric ischemia: JAK2 positivity and chronic active hepatitis B.

Mehmet Baykan1, Kürşat Gündoğan2, Hızır Yakup Akyıldız1, Mustafa Alper Yurci3.   

Abstract

Short bowel syndrome occurs as a result of insufficiency in the total length of the small intestine to provide adequate supply of nutrients. Seventy-five percent of cases are due to massive intestinal resection. A 35-year-old male complaining of abdominal pain was admitted to the gastroenterology department. A CT scan was performed, showing total occlusion of the portal vein and superior mesenteric vein. During the operation, widespread edema and necrosis of the small intestine were found. The necrotic segments of the small intestine were resected. The spleen was larger than normal and, in some parts, infarcts were evident, thus asplenectomy was also performed during surgery. A second-look procedure was performed 24 hours later, and an additional 10 cm jejunal resection and anastomosis was performed. His further evaluations revealed myeloproliferative disease and chronic active hepatitis B leading to thrombosis. Essential thrombocytosis and portal vein thrombosis are common in hepatitis B infection. Patients with complaints of abdominal pain in the context of essential thrombocytosis and hepatitis B should be handled with caution as they are at risk of developing portal vein thrombosis.

Entities:  

Keywords:  Portal vein thrombosis; hepatitis B; myeloproliferative disease

Year:  2013        PMID: 25931880      PMCID: PMC4379781          DOI: 10.5152/UCD.2013.1852

Source DB:  PubMed          Journal:  Ulus Cerrahi Derg        ISSN: 1300-0705


  10 in total

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Journal:  Gastroenterology       Date:  2000-05       Impact factor: 22.682

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Authors:  Stefan Acosta
Journal:  Semin Vasc Surg       Date:  2010-03       Impact factor: 1.000

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Authors:  Anca Florian; Ruxandra Jurcut; Ioana Lupescu; M Grasu; M Croitoru; Carmen Ginghină
Journal:  Rom J Intern Med       Date:  2010

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Authors:  Hiroshi Yasuhara
Journal:  Surg Today       Date:  2005       Impact factor: 2.549

5.  JAK2 mutation status, hemostatic risk factors and thrombophilic factors in essential thrombocythemia (ET) patients.

Authors:  Bożena Sokołowska; Aleksandra Nowaczyńska; Ksenia Bykowska; Sylwia Chocholska; Katarzyna Wejksza; Adam Walter-Croneck; Tomasz Gromek; Anna M Kowalska; Martyna Kandefer-Szerszeń; Anna Dmoszyńska
Journal:  Folia Histochem Cytobiol       Date:  2011       Impact factor: 1.698

Review 6.  Short bowel syndrome.

Authors:  J S Scolapio; C R Fleming
Journal:  Gastroenterol Clin North Am       Date:  1998-06       Impact factor: 3.806

7.  Anticardiolipin antibodies in chronic hepatitis B and chronic hepatitis D infection, and hepatitis B-related hepatocellular carcinoma. Relationship with portal vein thrombosis.

Authors:  Ioannis S Elefsiniotis; Ioannis D Diamantis; Spyros P Dourakis; Georgia Kafiri; Konstantinos Pantazis; Christos Mavrogiannis
Journal:  Eur J Gastroenterol Hepatol       Date:  2003-07       Impact factor: 2.566

8.  Undiagnosed myeloproliferative disease in cases of intra-abdominal thrombosis: the utility of the JAK2 617F mutation.

Authors:  Stephanie P'ng; Ben Carnley; Ross Baker; Nick Kontorinis; Wendy Cheng
Journal:  Clin Gastroenterol Hepatol       Date:  2008-03-07       Impact factor: 11.382

9.  High incidence of hepatitis B infection-associated cirrhosis and hepatocellular carcinoma in the Southeast Asian patients with portal vein thrombosis.

Authors:  Korn Lertpipopmetha; Chirayu U Auewarakul
Journal:  BMC Gastroenterol       Date:  2011-06-10       Impact factor: 3.067

Review 10.  JAK2 V617F: a single mutation in the myeloproliferative group of disorders.

Authors:  Donal McLornan; Melanie Percy; Mary Frances McMullin
Journal:  Ulster Med J       Date:  2006-05
  10 in total

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