Literature DB >> 25929402

[Active interventions in hypercholesteroloemia patients with high cardivascular risk in primary care].

Pedro J Tárraga López1, F J Garcia-Norro Herreros2, Loreto Tárraga Marcos3, Juan Solera Albero4, Esteban González López5, Antonio Ruiz García6, Vicente Pallarés Carratalá7, José Luis Castro Navarro8, Josep Alins Presas9, Josefa María Panisello Royo10.   

Abstract

INTRODUCTION: Hypercholesterolemia is a major modifiable risk factors for cardiovascular disease (CVD). Its reduction reduces morbidity and mortality from ischemic heart disease and CVD in general, primary prevention and secondary prevention especially.
OBJECTIVE: To determine whether a notarized and intensive clinical practice can overcome inertia and achieve the therapeutic goal (OT) LDL-C <100 mg / dL in high-risk patients attended in Primary Care (PC) in our country.
METHODOLOGY: epidemiological, prospective, multicenter study conducted in centers of different ACs By AP consecutive sampling 310 patients at high cardiovascular risk (diabetic or established CVD) previously treated with statins, which did not reach the OT included c-LDL.
RESULTS: The study subjects had a mean age of 65.2 years, of which 60.32% were male. The 41.64% had a previous EVC, acute myocardial infarction (20.33%), angina (16.07%), stroke / TIA (9.19%), arthropathy (5.25%), diabetes (70 , 87%), hypertension (71.01%), and abdominal obesity (69.62%). The 43.57% (95% CI: 37,21; 50,08) of patients who performed the 2nd visit (241) got the OT. 62.50% (95% CI: 55.68, 68.98) of those who took the 3rd (216) got the OT. Finally, 77.56% (95% CI: 72.13, 83.08) patients who performed the last visit (205) got the OT. Throughout the study there was a reduction in LDL-C levels from 135.6 mg / dL at baseline, 107.4 mg / dL in the 2nd visit, 97.3 mg / dL in the 3rd visit, up to 90.7 mg / dL at the final visit (p <0.0001) The increase in HDL-C from baseline (50.9 mg / dL) and final (53.6 mg / dL) was also significant (p = 0.013).
CONCLUSIONS: The reassessment and intensification of treatment in patients at high cardiovascular risk treated in primary care, applying the indications of the guides, achieves the OT in more than three quarters of the previously uncontrolled within half a year. These results should encourage us to overcome the therapeutic inertia in the control of CVD by early and energetic performance against hypercholesterolemia. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

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Year:  2015        PMID: 25929402     DOI: 10.3305/nh.2015.31.5.8795

Source DB:  PubMed          Journal:  Nutr Hosp        ISSN: 0212-1611            Impact factor:   1.057


  1 in total

1.  Association of Rs2071410 on Furin with Transient Ischemic Attack Susceptibility and Prognosis in a Chinese Population.

Authors:  Qin-Xiang Sun; Hai-Mei Zhou; Qing-Wei Du
Journal:  Med Sci Monit       Date:  2016-10-19
  1 in total

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