Literature DB >> 25928228

Role of mTOR-Chk1 in enhancing DNA-damaging therapy.

Jogitha Selvarajah, Abdeladim Moumen, Veronica A Carroll.   

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Year:  2015        PMID： 25928228      PMCID： PMC4612500          DOI： 10.1080/15384101.2015.1046790

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

Review 1.  mTOR signaling in growth control and disease.

Authors:  Mathieu Laplante; David M Sabatini
Journal:  Cell       Date:  2012-04-13       Impact factor: 41.582

2.  Inhibition of mTOR kinase by AZD8055 can antagonize chemotherapy-induced cell death through autophagy induction and down-regulation of p62/sequestosome 1.

Authors:  Shengbing Huang; Zhineng J Yang; Chunrong Yu; Frank A Sinicrope
Journal:  J Biol Chem       Date:  2011-09-23       Impact factor: 5.157

3.  mTOR regulates DNA damage response through NF-κB-mediated FANCD2 pathway in hematopoietic cells.

Authors:  J Li; W Du; S Zhang; F Guo; M O'Connor; G Thomas; S Kozma; B Zingarelli; Q Pang; Y Zheng
Journal:  Leukemia       Date:  2013-03-29       Impact factor: 11.528

4.  Regulation of FANCD2 by the mTOR pathway contributes to the resistance of cancer cells to DNA double-strand breaks.

Authors:  Changxian Shen; Duane Oswald; Doris Phelps; Hakan Cam; Christopher E Pelloski; Qishen Pang; Peter J Houghton
Journal:  Cancer Res       Date:  2013-04-30       Impact factor: 12.701

5.  TORC2-a new player in genome stability.

Authors:  Ronit Weisman; Adiel Cohen; Susan M Gasser
Journal:  EMBO Mol Med       Date:  2014-08       Impact factor: 12.137

6.  DNA damage-induced S and G2/M cell cycle arrest requires mTORC2-dependent regulation of Chk1.

Authors:  Jogitha Selvarajah; Androulla Elia; Veronica A Carroll; Abdeladim Moumen
Journal:  Oncotarget       Date:  2015-01-01

7.  Chemotherapy-mediated p53-dependent DNA damage response in clear cell renal cell carcinoma: role of the mTORC1/2 and hypoxia-inducible factor pathways.

Authors:  J Selvarajah; K Nathawat; A Moumen; M Ashcroft; V A Carroll
Journal:  Cell Death Dis       Date:  2013-10-17       Impact factor: 8.469
  7 in total
  1 in total

1.  mTORC1/2 and Protein Translation Regulate Levels of CHK1 and the Sensitivity to CHK1 Inhibitors in Ewing Sarcoma Cells.

Authors:  Stacia L Koppenhafer; Kelli L Goss; William W Terry; David J Gordon
Journal:  Mol Cancer Ther       Date:  2018-10-03       Impact factor: 6.261
  1 in total

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