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Literature DB >> 25927664

Flavonoids from Matteuccia struthiopteris and Their Anti-influenza Virus (H1N1) Activity.

Bo Li^1,2, Yang Ni¹, Ling-Juan Zhu¹, Feng-Bo Wu³, Fei Yan¹, Xue Zhang^1,4, Xin-Sheng Yao¹.

Abstract

Seven new flavonoid glycosides (1-7), matteflavosides A-G, together with 12 known flavonoids (8-19) were isolated from the rhizomes of Matteuccia struthiopteris (L.) Todar. Their structures were established via the analyses of extensive spectroscopic data. All compounds were evaluated for their anti-influenza virus (H1N1) activity using the neuraminidase inhibition assay. The results showed that compound 7 exhibited significant inhibitory activity against the H1N1 influenza virus neuraminidase with an EC50 value of 6.8 ± 1.1 μM and an SI value of 34.4, and compounds 8 and 17 showed moderate inhibitory activity.

Entities: Chemical Species

Mesh：

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Year: 2015 PMID： 25927664 DOI： 10.1021/np500879t

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

6 in total

6. Chemical Constituents from the Flower of Hosta plantaginea with Cyclooxygenases Inhibition and Antioxidant Activities and Their Chemotaxonomic Significance.

Authors: Li Yang; Shu-Tai Jiang; Qin-Guang Zhou; Guo-Yue Zhong; Jun-Wei He
Journal: Molecules Date: 2017-10-26 Impact factor: 4.411

6 in total

Flavonoids from Matteuccia struthiopteris and Their Anti-influenza Virus (H1N1) Activity.

1. Antiplasmodial flavanones and a stilbene from Carpha glomerata.

2. Anti-inflammatory and antioxidant activities of flavonoids from the flowers of Hosta plantaginea.

Review 3. Plant-Derived Natural Products as Lead Agents against Common Respiratory Diseases.

4. Neuraminidase Inhibitors from the Fruiting Body of Phellinus igniarius.

Review 5. Potential Natural Products Against Respiratory Viruses: A Perspective to Develop Anti-COVID-19 Medicines.

6. Chemical Constituents from the Flower of Hosta plantaginea with Cyclooxygenases Inhibition and Antioxidant Activities and Their Chemotaxonomic Significance.