Literature DB >> 25927109

Sedating drugs and breastfeeding.

Cheuk Kiu Chow, Gideon Koren.   

Abstract

QUESTION: If a mother takes a sedating drug during breastfeeding, will it cause central nervous system (CNS) depression in her breastfed baby? ANSWER: In some cases (eg, with the use of codeine or oxycodone) sedating drugs will likely cause CNS depression in breastfed infants and in other cases (eg, with the use of benzodiazepines) they will likely not. Mothers using sedating drugs should monitor their breastfed infants for signs of CNS depression (eg, drowsiness; difficulty breathing, feeding, or latching; or cyanosis), paradoxical effects (eg, unusual excitement,irritability), or inadequate weight gain.

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Year:  2015        PMID： 25927109      PMCID： PMC4369625     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN： 0008-350X            Impact factor:   3.275


  11 in total

Review 1.  Breastfeeding promotion for management of neonatal abstinence syndrome.

Authors:  Ursula A Pritham
Journal:  J Obstet Gynecol Neonatal Nurs       Date:  2013-09-04

2.  Pharmacogenetics of morphine poisoning in a breastfed neonate of a codeine-prescribed mother.

Authors:  Gideon Koren; James Cairns; David Chitayat; Andrea Gaedigk; Steven J Leeder
Journal:  Lancet       Date:  2006-08-19       Impact factor: 79.321

3.  Central nervous system depression of neonates breastfed by mothers receiving oxycodone for postpartum analgesia.

Authors:  Jessica Lam; Lauren Kelly; Catherine Ciszkowski; Marieke L A Landsmeer; Marieke Nauta; Bruce C Carleton; Michael R Hayden; Parvaz Madadi; Gideon Koren
Journal:  J Pediatr       Date:  2011-08-31       Impact factor: 4.406

4.  Neonatal benzodiazepines exposure during breastfeeding.

Authors:  Lauren E Kelly; Shirley Poon; Parvaz Madadi; Gideon Koren
Journal:  J Pediatr       Date:  2012-04-14       Impact factor: 4.406

5.  Breastfeeding reduces the need for withdrawal treatment in opioid-exposed infants.

Authors:  Gabrielle K Welle-Strand; Svetlana Skurtveit; Lauren M Jansson; Brittelise Bakstad; Lisa Bjarkø; Edle Ravndal
Journal:  Acta Paediatr       Date:  2013-09-02       Impact factor: 2.299

6.  Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication.

Authors:  S Ito; A Blajchman; M Stephenson; C Eliopoulos; G Koren
Journal:  Am J Obstet Gynecol       Date:  1993-05       Impact factor: 8.661

7.  Pharmacogenetics of neonatal opioid toxicity following maternal use of codeine during breastfeeding: a case-control study.

Authors:  P Madadi; C J D Ross; M R Hayden; B C Carleton; A Gaedigk; J S Leeder; G Koren
Journal:  Clin Pharmacol Ther       Date:  2008-08-20       Impact factor: 6.875

Review 8.  Guidelines for maternal codeine use during breastfeeding.

Authors:  Parvaz Madadi; Myla Moretti; Nada Djokanovic; Pina Bozzo; Irena Nulman; Shinya Ito; Gideon Koren
Journal:  Can Fam Physician       Date:  2009-11       Impact factor: 3.275

9.  Putative association of ABCB1 2677G>T/A with oxycodone-induced central nervous system depression in breastfeeding mothers.

Authors:  Jessica Lam; Lauren Kelly; Ilan Matok; Colin J D Ross; Bruce C Carleton; Michael R Hayden; Parvaz Madadi; Gideon Koren
Journal:  Ther Drug Monit       Date:  2013-08       Impact factor: 3.681

10.  A clinical tool for reducing central nervous system depression among neonates exposed to codeine through breast milk.

Authors:  Lauren E Kelly; Shahnaz A Chaudhry; Michael J Rieder; Geert 't Jong; Myla E Moretti; Andrea Lausman; Colin Ross; Howard Berger; Bruce Carleton; Michael R Hayden; Parvaz Madadi; Gideon Koren
Journal:  PLoS One       Date:  2013-07-29       Impact factor: 3.240
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  4 in total

1.  Transversus abdominis plane block with liposomal bupivacaine for pain control after cesarean delivery: a retrospective chart review.

Authors:  B Wycke Baker; Lea G Villadiego; Y Natasha Lake; Yazan Amin; Audra E Timmins; Laurie S Swaim; David W Ashton
Journal:  J Pain Res       Date:  2018-12-10       Impact factor: 3.133

2.  Opioid-Free Cesarean Section with Bilateral Quadratus Lumborum Catheters.

Authors:  Nadia Hernandez; Semhar J Ghebremichael; Sudipta Sen; Johanna B de Haan
Journal:  Local Reg Anesth       Date:  2020-02-07

3.  Effectiveness of wound site infiltration for parturients undergoing elective cesarean section in an Ethiopian hospital: A prospective cohort study.

Authors:  Dereje Zewdu; Temesgen Tantu; Meseret Olana; Diriba Teshome
Journal:  Ann Med Surg (Lond)       Date:  2021-03-29

4.  The Effectiveness and Safety of Intravenous Dexmedetomidine of Different Concentrations Combined with Butorphanol for Post-Caesarean Section Analgesia: A Randomized Controlled Trial.

Authors:  Shijiang Liu; Peipei Peng; Youli Hu; Cunming Liu; Xiaofei Cao; Chun Yang; Mei Gao
Journal:  Drug Des Devel Ther       Date:  2021-02-18       Impact factor: 4.162
  4 in total

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