Fernando Borges Pereira1, André Ferreira Leite2, Ana Patrícia de Paula3. 1. Faculdade de Ciências da Saúde, Universidade de Brasília, Brasília, DF, Brazil. 2. Faculdade de Ciências da Saúde, UnB, Brasília, DF, Brazil. 3. Hospital de Base de Brasília, Brasília, DF, Brazil.
Abstract
OBJECTIVE: Analyze the influence of sarcopenia in bone health of elderly men. SUBJECTS AND METHODS: This cross-sectional study evaluated 198 men aged over 60 years. Body composition was measured by dual energy X-ray absorptiometry. The BMD was measured at the femoral neck, total hip, lumbar spine and 33% radius. The diagnosis of abnormal BMD was defined for men who presented densitometric diagnosis of osteopenia or osteoporosis defined by T-score of femoral neck, total hip and lumbar spine. The pre-sarcopenia and sarcopenia were defined according to the European Working Group on Sarcopenia in Older People. RESULTS: The group diagnosed with normal BMD, compared to the group of abnormal BMD, have significantly higher body weight, body mass index, grip strength, lean mass, fat mass, and relative appendicular skeletal muscle mass (RASM). However, after multiple linear regression analysis, we found that only the RASM, lean mass, and handgrip strength in the dominant hand influenced the variability of the BMD after adjustment for age and weight. Regression analyzes showed a positive association between greater appendicular lean mass and a smaller number of elderly patients with abnormal BMD diagnostic. The regression analyzes showed that elderly men diagnosed with pre-sarcopenia and sarcopenia had more abnormal BMD than non-sarcopenic elderly men. CONCLUSION: We concluded that pre-sarcopenia and sarcopenia were associated with abnormal BMD. The lean mass, compared to fat mass, has a greater positive influence on the BMD of elderly men. This result suggests the importance of the increase in lean mass for the bone health of elderly men.
OBJECTIVE: Analyze the influence of sarcopenia in bone health of elderly men. SUBJECTS AND METHODS: This cross-sectional study evaluated 198 men aged over 60 years. Body composition was measured by dual energy X-ray absorptiometry. The BMD was measured at the femoral neck, total hip, lumbar spine and 33% radius. The diagnosis of abnormal BMD was defined for men who presented densitometric diagnosis of osteopenia or osteoporosis defined by T-score of femoral neck, total hip and lumbar spine. The pre-sarcopenia and sarcopenia were defined according to the European Working Group on Sarcopenia in Older People. RESULTS: The group diagnosed with normal BMD, compared to the group of abnormal BMD, have significantly higher body weight, body mass index, grip strength, lean mass, fat mass, and relative appendicular skeletal muscle mass (RASM). However, after multiple linear regression analysis, we found that only the RASM, lean mass, and handgrip strength in the dominant hand influenced the variability of the BMD after adjustment for age and weight. Regression analyzes showed a positive association between greater appendicular lean mass and a smaller number of elderly patients with abnormal BMD diagnostic. The regression analyzes showed that elderly men diagnosed with pre-sarcopenia and sarcopenia had more abnormal BMD than non-sarcopenic elderly men. CONCLUSION: We concluded that pre-sarcopenia and sarcopenia were associated with abnormal BMD. The lean mass, compared to fat mass, has a greater positive influence on the BMD of elderly men. This result suggests the importance of the increase in lean mass for the bone health of elderly men.
Authors: Pratima Sharma; Neehar D Parikh; Jessica Yu; Pranab Barman; Brian A Derstine; Christopher J Sonnenday; Stewart C Wang; Grace L Su Journal: Liver Transpl Date: 2016-06-29 Impact factor: 5.799
Authors: Joao Pedro Pinho; Arturo Forner-Cordero; Rosa Maria Rodrigues Pereira; Arnaldo Jose Hernandez; Egidio Lima Dorea; Bruno Mezencio; Liliam Takayama; Jackeline Couto Alvarenga; Julio Cerca Serrao; Alberto Carlos Amadio Journal: IEEE J Transl Eng Health Med Date: 2020-01-03 Impact factor: 3.316