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Literature DB >> 2592544

Detection of the 43,000-molecular-weight glycoprotein in sera of patients with paracoccidioidomycosis.

M J Mendes-Giannini¹, J P Bueno, M A Shikanai-Yasuda, A W Ferreira, A Masuda.

Abstract

The 43,000-molecular-weight (43K) soluble glycoprotein was detected in sera of patients with paracoccidioidomycosis by the immunoblot technique by using as the probe rabbit monospecific antisera to this fraction. The 43K antigen was present before treatment in sera of patients with the acute (juvenile) form; it started to disappear from circulation after 10 months of chemotherapy, and it was undetectable after 2 years of treatment. In the chronic cases, the 43K antigen was detected in patients without treatment, and it was absent in the healed cases. The detection of the 43K protein specific to Paracoccidioides brasiliensis may be important for its diagnostic value as well as for modulation of the host immune response.

Entities: Disease Species

Mesh：

Substances：

Year: 1989 PMID： 2592544 PMCID： PMC267138 DOI： 10.1128/jcm.27.12.2842-2845.1989

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

25 in total

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31 in total

1. PCR for diagnosis of paracoccidioidomycosis.

Authors: G M Gomes; P S Cisalpino; C P Taborda; Z P de Camargo
Journal: J Clin Microbiol Date: 2000-09 Impact factor: 5.948

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Authors: M C Z Perenha-Viana; I A A Gonzales; S R Brockelt; L N C Machado; T I E Svidzinski
Journal: Clin Vaccine Immunol Date: 2012-02-01

3. T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals.

Authors: Leo Kei Iwai; Márcia Yoshida; Aya Sadahiro; Washington Robert da Silva; Maria Lucia Marin; Anna Carla Goldberg; Maria Aparecida Juliano; Luiz Juliano; Maria Aparecida Shikanai-Yasuda; Jorge Kalil; Edecio Cunha-Neto; Luiz R Travassos
Journal: Clin Vaccine Immunol Date: 2007-02-28

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Authors: Zoilo Pires de Camargo
Journal: Mycopathologia Date: 2008 Apr-May Impact factor: 2.574

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Journal: J Clin Microbiol Date: 1998-06 Impact factor: 5.948

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Authors: Vanessa G Batista; Marcos S Toledo; Anita H Straus; Maria J S Mendes-Giannini; Alberto J S Duarte; Helio K Takahashi; Gil Benard
Journal: Mycopathologia Date: 2014-07-16 Impact factor: 2.574

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Journal: J Clin Microbiol Date: 2002-02 Impact factor: 5.948

9. Combined use of Paracoccidioides brasiliensis recombinant 27-kilodalton and purified 87-kilodalton antigens in an enzyme-linked immunosorbent assay for serodiagnosis of paracoccidioidomycosis.

Authors: Soraya Díez; Beatriz L Gómez; Juan G McEwen; Angela Restrepo; Rod J Hay; Andrew J Hamilton
Journal: J Clin Microbiol Date: 2003-04 Impact factor: 5.948

10. Evaluation of Paracoccidioides brasiliensis infection by gp 43 intradermal test in rural settlements in Central-West Brazil.

Authors: Ana Paula da C Marques; Sandra Maria V L Oliveira; Grazielli R Rezende; Dayane A Melo; Sonia M Fernandes-Fitts; Elenir Rose J C Pontes; Maria da Glória Bonecini-Almeida; Zoilo P Camargo; Anamaria M M Paniago
Journal: Mycopathologia Date: 2013-04-24 Impact factor: 2.574