Literature DB >> 25923897

Antifungal activity of silver nanoparticles obtained by green synthesis.

Eduardo José J Mallmann1, Francisco Afrânio Cunha1, Bruno N M F Castro2, Auberson Martins Maciel1, Everardo Albuquerque Menezes2, Pierre Basílio Almeida Fechine1.   

Abstract

Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment.

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Year:  2015        PMID： 25923897      PMCID： PMC4435016          DOI： 10.1590/S0036-46652015000200011

Source DB:  PubMed          Journal:  Rev Inst Med Trop Sao Paulo        ISSN： 0036-4665            Impact factor:   1.846


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