| Literature DB >> 25923102 |
Dorota Szcześniak1, Aleksandra Jawiarczyk-Przybyłowska2, Joanna Rymaszewska1.
Abstract
Acromegaly is a rare and chronic disease, most often caused by a pituitary adenoma. Excessive secretion of the growth hormone (GH) leads to hepatic secretion of insulin-like growth factor-1 (IGF-1), which in turn causes characteristic changes in the patient's appearance, many skeletal deformities and metabolic disorders. In addition to somatic symptoms, acromegalic patients demonstrate psychosocial and personality deficits, as well as common co-occurrence of mental disorders. There are few studies investigating acromegaly in Poland. In recent years, the concept of quality of life has become fundamental to understanding health problems. Studies dealing with acromegaly likewise tend to include assessments of quality of life of patients suffering from this endocrinopathy.Entities:
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Year: 2015 PMID: 25923102 DOI: 10.17219/acem/38156
Source DB: PubMed Journal: Adv Clin Exp Med ISSN: 1899-5276 Impact factor: 1.727