Kenji Obayashi1, Keigo Saeki2, Norio Kurumatani2. 1. Department of Community Health and Epidemiology, Nara Medical University School of Medicine, Nara, Japan. Electronic address: obayashi@naramed-u.ac.jp. 2. Department of Community Health and Epidemiology, Nara Medical University School of Medicine, Nara, Japan.
Abstract
OBJECTIVE: A significant association between nocturia and subjective sleep quality has previously been reported; however, the association between nocturia and objective sleep quality remains unclear. The purpose of this study was to evaluate the quantitative association between nocturnal voiding (NV) frequency and objective sleep quality in a large, general, elderly population. METHODS: Nocturnal voiding frequency, objective sleep quality, and subjective sleep quality were measured among 1086 community-based elderly individuals using actigraphy and the Pittsburgh Sleep Quality Index (PSQI) questionnaire. RESULTS: In multivariate analyses adjusted for potential confounding factors (such as age, gender, body mass index, medication use, renal function, bedtime, rising time, daytime physical activity, endogenous melatonin levels, and bedroom light levels), increased NV frequency, ranging from zero, one, two, three or more voids, was significantly associated with poorer objective sleep quality, including lower sleep efficiency (SE) and longer wake after sleep onset (WASO) (mean SE, 86.3, 84.8, 83.6, and 81.2%, respectively; p for trend <0.001; mean WASO: 42.6, 49.0, 53.6, and 66.1 min, respectively; p for trend <0.001), but shorter sleep onset latency (SOL) (mean SOL, 3.0, 3.0, 2.8, and 2.8 log min, respectively; p for trend = 0.018). In addition, an increased NV frequency was significantly associated with poorer subjective sleep quality in a multivariate model (mean PSQI global score, 4.60, 4.86, 5.22, and 5.48, respectively; p for trend 0.012). CONCLUSION: The present study revealed a quantitative association between NV frequency and objective sleep quality in the general elderly population.
OBJECTIVE: A significant association between nocturia and subjective sleep quality has previously been reported; however, the association between nocturia and objective sleep quality remains unclear. The purpose of this study was to evaluate the quantitative association between nocturnal voiding (NV) frequency and objective sleep quality in a large, general, elderly population. METHODS: Nocturnal voiding frequency, objective sleep quality, and subjective sleep quality were measured among 1086 community-based elderly individuals using actigraphy and the Pittsburgh Sleep Quality Index (PSQI) questionnaire. RESULTS: In multivariate analyses adjusted for potential confounding factors (such as age, gender, body mass index, medication use, renal function, bedtime, rising time, daytime physical activity, endogenous melatonin levels, and bedroom light levels), increased NV frequency, ranging from zero, one, two, three or more voids, was significantly associated with poorer objective sleep quality, including lower sleep efficiency (SE) and longer wake after sleep onset (WASO) (mean SE, 86.3, 84.8, 83.6, and 81.2%, respectively; p for trend <0.001; mean WASO: 42.6, 49.0, 53.6, and 66.1 min, respectively; p for trend <0.001), but shorter sleep onset latency (SOL) (mean SOL, 3.0, 3.0, 2.8, and 2.8 log min, respectively; p for trend = 0.018). In addition, an increased NV frequency was significantly associated with poorer subjective sleep quality in a multivariate model (mean PSQI global score, 4.60, 4.86, 5.22, and 5.48, respectively; p for trend 0.012). CONCLUSION: The present study revealed a quantitative association between NV frequency and objective sleep quality in the general elderly population.
Authors: William D Winkelman; Ann Warsi; Alison J Huang; Michael Schembri; Rebecca G Rogers; Holly E Richter; Deborah L Myers; Stephen R Kraus; Karen C Johnson; Rachel Hess; Thomas Gregory; Catherine S Bradley; Lily A Arya; Jeanette S Brown; Katie L Stone; Leslee L Subak Journal: Female Pelvic Med Reconstr Surg Date: 2018 Mar/Apr Impact factor: 2.091
Authors: Constance H Fung; Camille P Vaughan; Alayne D Markland; Alison J Huang; Michael N Mitchell; Donald L Bliwise; Sonia Ancoli-Israel; Susan Redline; Cathy A Alessi; Katie Stone Journal: J Am Geriatr Soc Date: 2017-09-15 Impact factor: 5.562