Literature DB >> 2591961

Twenty loci form a continuous linkage map of markers for human chromosome 2.

P O'Connell1, G M Lathrop, Y Nakamura, M L Leppert, J M Lalouel, R White.   

Abstract

We have used a combination of 20 DNA markers and 1 protein electromorph, defining 20 loci, to construct a genetic linkage map of chromosome 2. These markers form a continuous linkage group of 306 cM in males and 529 cM in females. Female map distances varied from approximately twofold higher to equivalence from those of males across the map. Among the DNA markers are six well-distributed, highly polymorphic markers reflecting loci that contain a variable number of tandem repeats that will be highly efficient anchor points for the eventual application of this map to studies of human genetic disease.

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Year:  1989        PMID： 2591961     DOI： 10.1016/0888-7543(89)90115-8

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  9 in total

Review 1.  Mouse chromosome 12.

Authors:  P D'Eustachio
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 2.  Mouse chromosome 12.

Authors:  P D'Eustachio
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

3.  1989 Allen Award address: the American Society of Human Genetics annual meeting, Baltimore.

Authors:  R White
Journal:  Am J Hum Genet       Date:  1990-12       Impact factor: 11.025

4.  No proof of linkage between schizophrenia-related disorders including schizophrenia and chromosome 2q21 region.

Authors:  H N Aschauer; G Fischer; K E Isenberg; K Meszaros; U Willinger; R D Todd; H Beran; R Strobl; M Lang; K Fuchs
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  1993       Impact factor: 5.270

5.  The human vigilin gene: identification, chromosomal localization and expression pattern.

Authors:  G Plenz; S Kügler; S Schnittger; H Rieder; C Fonatsch; P K Müller
Journal:  Hum Genet       Date:  1994-05       Impact factor: 4.132

6.  Exclusion of familial dysautonomia from more than 60% of the genome.

Authors:  A Blumenfeld; F B Axelrod; J A Trofatter; C Maayan; D E Lucente; S A Slaugenhaupt; C B Liebert; L J Ozelius; J L Haines; X O Breakefield
Journal:  J Med Genet       Date:  1993-01       Impact factor: 6.318

7.  Assignment of the locus for Waardenburg syndrome type I to human chromosome 2q37 and possible homology to the Splotch mouse.

Authors:  C Foy; V Newton; D Wellesley; R Harris; A P Read
Journal:  Am J Hum Genet       Date:  1990-06       Impact factor: 11.025

8.  Waardenburg syndrome (WS) type I is caused by defects at multiple loci, one of which is near ALPP on chromosome 2: first report of the WS consortium.

Authors:  L A Farrer; K M Grundfast; J Amos; K S Arnos; J H Asher; P Beighton; S R Diehl; J Fex; C Foy; T B Friedman
Journal:  Am J Hum Genet       Date:  1992-05       Impact factor: 11.025

9.  A genome-wide search for genes predisposing to manic-depression, assuming autosomal dominant inheritance.

Authors:  H Coon; S Jensen; M Hoff; J Holik; R Plaetke; F Reimherr; P Wender; M Leppert; W Byerley
Journal:  Am J Hum Genet       Date:  1993-06       Impact factor: 11.025
  9 in total

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