Literature DB >> 25918215

Failure of ivermectin per rectum to achieve clinically meaningful serum levels in two cases of Strongyloides hyperinfection.

Isaac I Bogoch1, Kamran Khan2, Howard Abrams2, Caroline Nott2, Elizabeth Leung2, Lawrence Fleckenstein2, Jay S Keystone2.   

Abstract

Two cases of Strongyloides hyperinfection are presented. Ivermectin was initially administered orally and per rectum pending the availability of subcutaneous (SC) preparations. In neither case did rectal suppositories of ivermectin achieve clinically meaningful serum values. Clinicians should use SC preparations of ivermectin as early as possible in Strongyloides hyperinfection and dissemination. © The American Society of Tropical Medicine and Hygiene.

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Year:  2015        PMID： 25918215      PMCID： PMC4497912          DOI： 10.4269/ajtmh.15-0077

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  16 in total

1.  Parenteral ivermectin in Strongyloides hyperinfection.

Authors:  P L Chiodini; A J Reid; M J Wiselka; R Firmin; J Foweraker
Journal:  Lancet       Date:  2000-01-01       Impact factor: 79.321

2.  Safety, tolerability, and pharmacokinetics of escalating high doses of ivermectin in healthy adult subjects.

Authors:  Cynthia A Guzzo; Christine I Furtek; Arturo G Porras; Cong Chen; Robert Tipping; Coleen M Clineschmidt; David G Sciberras; John Y K Hsieh; Kenneth C Lasseter
Journal:  J Clin Pharmacol       Date:  2002-10       Impact factor: 3.126

3.  Paralytic ileus due to strongyloidiasis: case report and review of the literature.

Authors:  D Nonaka; K Takaki; M Tanaka; M Umeno; T Takeda; M Yoshida; Y Haraguch; K Okada; Y Sawae
Journal:  Am J Trop Med Hyg       Date:  1998-10       Impact factor: 2.345

4.  Subcutaneous ivermectin as a safe salvage therapy in Strongyloides stercoralis hyperinfection syndrome: a case report.

Authors:  Jerome Pacanowski; Marie Dos Santos; Antoine Roux; Christine LE Maignan; Jacques Guillot; Veronique Lavarde; Muriel Cornet
Journal:  Am J Trop Med Hyg       Date:  2005-07       Impact factor: 2.345

5.  Treatment of human disseminated strongyloidiasis with a parenteral veterinary formulation of ivermectin.

Authors:  Francisco M Marty; Colleen M Lowry; Martin Rodriguez; Danny A Milner; Walter S Pieciak; Anushua Sinha; Lawrence Fleckenstein; Lindsey R Baden
Journal:  Clin Infect Dis       Date:  2005-05-11       Impact factor: 9.079

6.  Nematocidal activities of thiabendazole and ivermectin against the larvae of Strongyloides ratti and S. venezuelensis.

Authors:  T Satou; M Koga; K Koike; I Tada; T Nikaido
Journal:  Vet Parasitol       Date:  2001-08-31       Impact factor: 2.738

7.  Predictive markers for development of strongyloidiasis in patients infected with both Strongyloides stercoralis and HTLV-1.

Authors:  M Satoh; S Kiyuna; Y Shiroma; H Toma; A Kokaze; Y Sato
Journal:  Clin Exp Immunol       Date:  2003-09       Impact factor: 4.330

8.  Case report: Rectal adminstration of ivermectin to a patient with Strongyloides hyperinfection syndrome.

Authors:  Philip E Tarr; Peter S Miele; Kenneth S Peregoy; Margo A Smith; Franklin A Neva; Daniel R Lucey
Journal:  Am J Trop Med Hyg       Date:  2003-04       Impact factor: 2.345

9.  Treatment of Strongyloides stercoralis hyperinfection syndrome with thiabendazole administered per rectum.

Authors:  D J Boken; P A Leoni; L C Preheim
Journal:  Clin Infect Dis       Date:  1993-01       Impact factor: 9.079

10.  Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin.

Authors:  H P Hauber; J Galle; P L Chiodini; J Rupp; R Birke; E Vollmer; P Zabel; C Lange
Journal:  Infection       Date:  2005-10       Impact factor: 3.553
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  2 in total

1.  Case Report: Ivermectin and Albendazole Plasma Concentrations in a Patient with Disseminated Strongyloidiasis on Extracorporeal Membrane Oxygenation and Continuous Renal Replacement Therapy.

Authors:  Carl Boodman; Yashpal S Chhonker; Daryl J Murry; Allison Mah; Jennifer Grant; Theodore Steiner; Michael Libman; Cesilia Nishi; Marthe Charles
Journal:  Am J Trop Med Hyg       Date:  2018-11       Impact factor: 2.345

2.  Successful use of subcutaneous ivermectin for the treatment of Strongyloides stercoralis hyperinfection in the setting of small bowel obstruction and paralytic ileus in the immunocompromised population.

Authors:  Kristen Zeitler; Ripal Jariwala; Ricardo Restrepo-Jaramillo; Shyam Kapadia; Beata Casanas; Sally Alrabaa; Chakrapol Sriaroon
Journal:  BMJ Case Rep       Date:  2018-06-04
  2 in total

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