Literature DB >> 25917937

Biocontainment through reengineered genetic codes.

Arjun Ravikumar1, Chang C Liu2.   

Abstract

It's only unnatural: Reengineered genetic codes can achieve biocontainment by specifying different meanings for protein sequences in modified versus natural organisms; the synthetic bacterium discussed here is dependent on unnatural amino acids because its reengineered genetic code specifies unnatural amino acids in essential genes.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords:  amino acids; biocontainment; genetic code; genome engineering; microbes; synthetic biology

Mesh：

Year:  2015        PMID： 25917937     DOI： 10.1002/cbic.201500157

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


  7 in total

1.  Mutually Orthogonal DNA Replication Systems In Vivo.

Authors:  Garri A Arzumanyan; Kristin N Gabriel; Arjun Ravikumar; Alex A Javanpour; Chang C Liu
Journal:  ACS Synth Biol       Date:  2018-07-10       Impact factor: 5.110

2.  Fail-safe genetic codes designed to intrinsically contain engineered organisms.

Authors:  Jonathan Calles; Isaac Justice; Detravious Brinkley; Alexa Garcia; Drew Endy
Journal:  Nucleic Acids Res       Date:  2019-11-04       Impact factor: 16.971

3.  Bottlenecks and opportunities for synthetic biology biosafety standards.

Authors:  Lei Pei; Michele Garfinkel; Markus Schmidt
Journal:  Nat Commun       Date:  2022-04-21       Impact factor: 17.694

4.  Codon reassignment to facilitate genetic engineering and biocontainment in the chloroplast of Chlamydomonas reinhardtii.

Authors:  Rosanna E B Young; Saul Purton
Journal:  Plant Biotechnol J       Date:  2015-10-15       Impact factor: 9.803

5.  Diverse protein manipulations with genetically encoded glutamic acid benzyl ester.

Authors:  Xiaochen Yang; Hui Miao; Ruotong Xiao; Luyao Wang; Yan Zhao; Qifan Wu; Yanli Ji; Juanjuan Du; Hongqiang Qin; Weimin Xuan
Journal:  Chem Sci       Date:  2021-06-17       Impact factor: 9.825

Review 6.  Targeted mutagenesis: A sniper-like diversity generator in microbial engineering.

Authors:  Xiang Zheng; Xin-Hui Xing; Chong Zhang
Journal:  Synth Syst Biotechnol       Date:  2017-07-14

7.  A genetically engineered Escherichia coli that senses and degrades tetracycline antibiotic residue.

Authors:  Zepeng Mu; Zhuoning Zou; Ye Yang; Wenbo Wang; Yue Xu; Jianyi Huang; Ruiling Cai; Ye Liu; Yajin Mo; Boyi Wang; Yiqun Dang; Yongming Li; Yushan Liu; Yueren Jiang; Qingyang Tan; Xiaohong Liu; Cheng Hu; Hua Li; Sha Wei; Chunbo Lou; Yang Yu; Jiangyun Wang
Journal:  Synth Syst Biotechnol       Date:  2018-05-31
  7 in total

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