Literature DB >> 25917806

Sore throat: Is it such a big deal anymore?

Verangi C K Herath1, Jonathan Carapetis2.   

Abstract

Sore throat remains a common disease of childhood, and a major cost and cause for antibiotic prescriptions. The management of sore throat remains controversial in affluent countries with various guidelines available and overall poor adherence to those guidelines. Group A streptococcus is the commonest bacterial cause with important sequelae including acute rheumatic fever (ARF). The driver for diagnosis and treatment is still questionable. In most affluent populations it is difficult to justify antibiotic treatment on the basis of preventing ARF, whereas this remains the major driver for sore throat management in populations at higher risk of ARF. Reduction in severity and duration of symptoms may be a reasonable basis to consider antibiotic treatment, and thus accurate diagnosis of GAS pharyngitis, particularly in those with more severe symptoms. The potential role of rapid tests in diagnosis appears to be increasing.
Copyright © 2015 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Antibiotic; Bacterial; Child; Diagnosis; Pharyngitis; Sore throat; Treatment

Mesh:

Substances:

Year:  2015        PMID: 25917806     DOI: 10.1016/j.jinf.2015.04.010

Source DB:  PubMed          Journal:  J Infect        ISSN: 0163-4453            Impact factor:   6.072


  4 in total

1.  Appropriateness of diagnosis of streptococcal pharyngitis among Thai community pharmacists according to the Centor criteria.

Authors:  Woranuch Saengcharoen; Pornchanok Jaisawang; Palita Udomcharoensab; Kittika Buathong; Sanguan Lerkiatbundit
Journal:  Int J Clin Pharm       Date:  2016-08-29

Review 2.  Corticosteroids for treatment of sore throat: systematic review and meta-analysis of randomised trials.

Authors:  Behnam Sadeghirad; Reed A C Siemieniuk; Romina Brignardello-Petersen; Davide Papola; Lyubov Lytvyn; Per Olav Vandvik; Arnaud Merglen; Gordon H Guyatt; Thomas Agoritsas
Journal:  BMJ       Date:  2017-09-20

3.  Aetiology of febrile pharyngitis in children: Potential of myxovirus resistance protein A (MxA) as a biomarker of viral infection.

Authors:  Lauri Ivaska; Jussi Niemelä; Johanna Lempainen; Riikka Österback; Matti Waris; Tytti Vuorinen; Jukka Hytönen; Kaisu Rantakokko-Jalava; Ville Peltola
Journal:  J Infect       Date:  2017-01-07       Impact factor: 6.072

4.  The feasibility of measuring calprotectin from a throat swab as a marker of infections caused by group A streptococcus: a case-control feasibility study.

Authors:  Behnaz Schofield; Clive Gregory; Micaela Gal; David Gillespie; Gurudutt Naik; Alastair Hay; Nick Francis
Journal:  BJGP Open       Date:  2020-06-23
  4 in total

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