| Literature DB >> 25917334 |
Shi Hyoung Kim1, Jae Gwang Park1, Gi-Ho Sung2,3, Sungjae Yang1, Woo Seok Yang1, Eunji Kim1, Jun Ho Kim1, Van Thai Ha1, Han Gyung Kim1, Young-Su Yi1, Ji Hye Kim1, Kwang-Soo Baek1, Nak Yoon Sung1, Mi-nam Lee4, Jong-Hoon Kim5, Jae Youl Cho1.
Abstract
Kaempferol (KF) is the most abundant polyphenol in tea, fruits, vegetables, and beans. However, little is known about its in vivo anti-inflammatory efficacy and mechanisms of action. To study these, several acute mouse inflammatory and nociceptive models, including gastritis, pancreatitis, and abdominal pain were employed. Kaempferol was shown to attenuate the expansion of inflammatory lesions seen in ethanol (EtOH)/HCl- and aspirin-induced gastritis, LPS/caerulein (CA) triggered pancreatitis, and acetic acid-induced writhing.Entities:
Keywords: Abdominal pain; Anti-inflammatory effect; Gastritis; Kaempferol; Pancreatitis
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Year: 2015 PMID： 25917334 DOI： 10.1002/mnfr.201400820
Source DB: PubMed Journal: Mol Nutr Food Res ISSN： 1613-4125 Impact factor: 5.914