Literature DB >> 25917131

Structure of the K6 capsular polysaccharide from Acinetobacter baumannii isolate RBH4.

Johanna J Kenyon1, Alberto M Marzaioli2, Ruth M Hall1, Cristina De Castro3.   

Abstract

The structure of the capsular polysaccharide (CPS) from an Acinetobacter baumannii global clone 2 (GC2) clinical isolate RBH4 that carries the KL6 gene cluster was elucidated by means of chemical and spectroscopical methods. The repeating unit of K6 CPS is linear and contains N-acetyl-D-galactosamine (D-GalpNAc), two D-galactose (D-Galp) residues and 5,7-di-N-acetylpseudaminic acid (Pse5Ac7Ac). The synthesis of these sugars could be attributed to genes in the KL6 capsule biosynthesis gene cluster, and the formation of the linkages between the sugars were assigned to glycosyltransferases or the Wzy polymerase encoded in KL6.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Capsular polysaccharide; K locus; KL6 gene cluster; NMR spectroscopy; Pseudaminic acid

Mesh：

Substances：

Year:  2015        PMID： 25917131     DOI： 10.1016/j.carres.2015.03.016

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN： 0008-6215            Impact factor:   2.104


  5 in total

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Authors:  Daniel Wibberg; Ileana P Salto; Felix G Eikmeyer; Irena Maus; Anika Winkler; Patrice Nordmann; Alfred Pühler; Laurent Poirel; Andreas Schlüter
Journal:  Antimicrob Agents Chemother       Date:  2018-04-26       Impact factor: 5.191

2.  Involvement of a Phage-Encoded Wzy Protein in the Polymerization of K127 Units To Form the Capsular Polysaccharide of Acinetobacter baumannii Isolate 36-1454.

Authors:  Ruth M Hall; Yuriy A Knirel; Johanna J Kenyon; Nikolay P Arbatsky; Anastasiya A Kasimova; Alexander S Shashkov; Mikhail M Shneider; Anastasiya V Popova; Dmitry A Shagin; Andrey A Shelenkov; Yuliya V Mikhailova; Yurii G Yanushevich
Journal:  Microbiol Spectr       Date:  2022-04-27

3.  Structure of the K12 capsule containing 5,7-di-N-acetylacinetaminic acid from Acinetobacter baumannii isolate D36.

Authors:  Johanna J Kenyon; Alberto M Marzaioli; Ruth M Hall; Cristina De Castro
Journal:  Glycobiology       Date:  2015-04-28       Impact factor: 4.313

4.  The K46 and K5 capsular polysaccharides produced by Acinetobacter baumannii NIPH 329 and SDF have related structures and the side-chain non-ulosonic acids are 4-O-acetylated by phage-encoded O-acetyltransferases.

Authors:  Johanna J Kenyon; Nikolay P Arbatsky; Mikhail M Shneider; Anastasiya V Popova; Andrei S Dmitrenok; Anastasiya A Kasimova; Alexander S Shashkov; Ruth M Hall; Yuriy A Knirel
Journal:  PLoS One       Date:  2019-06-20       Impact factor: 3.240

5.  Specific Interaction of Novel Friunavirus Phages Encoding Tailspike Depolymerases with Corresponding Acinetobacter baumannii Capsular Types.

Authors:  A V Popova; M M Shneider; N P Arbatsky; A A Kasimova; S N Senchenkova; A S Shashkov; A S Dmitrenok; A O Chizhov; Y V Mikhailova; D A Shagin; O S Sokolova; O Y Timoshina; R S Kozlov; K A Miroshnikov; Y A Knirel
Journal:  J Virol       Date:  2020-12-02       Impact factor: 5.103
  5 in total

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