Literature DB >> 25916514

FASTKD2 and human memory: functional pathways and prospects for novel therapeutic target development for Alzheimer's disease and age-associated memory decline.

Vijay K Ramanan1, Andrew J Saykin.   

Abstract

Entities:  

Keywords:  Alzheimer's disease; FASTKD2; apoptosis; cognitive aging; drug target; fas-associated serine/threonine kinase domains 2; functional genomics; inflammation; memory; microRNA; mitochondria

Mesh：

Substances：

Year:  2015        PMID： 25916514      PMCID： PMC4478049          DOI： 10.2217/pgs.15.8

Source DB:  PubMed          Journal:  Pharmacogenomics        ISSN： 1462-2416            Impact factor:   2.533


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  20 in total

1.  FAST is a survival protein that senses mitochondrial stress and modulates TIA-1-regulated changes in protein expression.

Authors:  Wei Li; Maria Simarro; Nancy Kedersha; Paul Anderson
Journal:  Mol Cell Biol       Date:  2004-12       Impact factor: 4.272

2.  Fas-activated serine/threonine phosphoprotein promotes immune-mediated pulmonary inflammation.

Authors:  Maria Simarro; Giorgio Giannattasio; Miguel A De la Fuente; Charaf Benarafa; Kulandayan K Subramanian; Rumey Ishizawar; Barbara Balestrieri; Emma M Andersson; Hongbo R Luo; Antonio Orduña; Joshua Boyce; Paul Anderson
Journal:  J Immunol       Date:  2010-04-02       Impact factor: 5.422

Review 3.  Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases.

Authors:  Michael T Lin; M Flint Beal
Journal:  Nature       Date:  2006-10-19       Impact factor: 49.962

4.  TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha.

Authors:  M Piecyk; S Wax; A R Beck; N Kedersha; M Gupta; B Maritim; S Chen; C Gueydan; V Kruys; M Streuli; P Anderson
Journal:  EMBO J       Date:  2000-08-01       Impact factor: 11.598

5.  Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.

Authors:  Alfredo Castello; Bernd Fischer; Katrin Eichelbaum; Rastislav Horos; Benedikt M Beckmann; Claudia Strein; Norman E Davey; David T Humphreys; Thomas Preiss; Lars M Steinmetz; Jeroen Krijgsveld; Matthias W Hentze
Journal:  Cell       Date:  2012-05-31       Impact factor: 41.582

Review 6.  Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders.

Authors:  Vijay K Ramanan; Andrew J Saykin
Journal:  Am J Neurodegener Dis       Date:  2013-09-18

7.  Spatio-temporal transcriptome of the human brain.

Authors:  Hyo Jung Kang; Yuka Imamura Kawasawa; Feng Cheng; Ying Zhu; Xuming Xu; Mingfeng Li; André M M Sousa; Mihovil Pletikos; Kyle A Meyer; Goran Sedmak; Tobias Guennel; Yurae Shin; Matthew B Johnson; Zeljka Krsnik; Simone Mayer; Sofia Fertuzinhos; Sheila Umlauf; Steven N Lisgo; Alexander Vortmeyer; Daniel R Weinberger; Shrikant Mane; Thomas M Hyde; Anita Huttner; Mark Reimers; Joel E Kleinman; Nenad Sestan
Journal:  Nature       Date:  2011-10-26       Impact factor: 49.962

Review 8.  The genetics of Leigh syndrome and its implications for clinical practice and risk management.

Authors:  Ilene S Ruhoy; Russell P Saneto
Journal:  Appl Clin Genet       Date:  2014-11-13

9.  Fas Activated Serine-Threonine Kinase Domains 2 (FASTKD2) mediates apoptosis of breast and prostate cancer cells through its novel FAST2 domain.

Authors:  Sharmistha Das; Kay T Yeung; Muktar A Mahajan; Herbert H Samuels
Journal:  BMC Cancer       Date:  2014-11-20       Impact factor: 4.430

10.  Exome sequencing in undiagnosed inherited and sporadic ataxias.

Authors:  Angela Pyle; Tania Smertenko; David Bargiela; Helen Griffin; Jennifer Duff; Marie Appleton; Konstantinos Douroudis; Gerald Pfeffer; Mauro Santibanez-Koref; Gail Eglon; Patrick Yu-Wai-Man; Venkateswaran Ramesh; Rita Horvath; Patrick F Chinnery
Journal:  Brain       Date:  2014-12-12       Impact factor: 13.501
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  3 in total

Review 1.  Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans.

Authors:  Andrew J Saykin; Li Shen; Xiaohui Yao; Sungeun Kim; Kwangsik Nho; Shannon L Risacher; Vijay K Ramanan; Tatiana M Foroud; Kelley M Faber; Nadeem Sarwar; Leanne M Munsie; Xiaolan Hu; Holly D Soares; Steven G Potkin; Paul M Thompson; John S K Kauwe; Rima Kaddurah-Daouk; Robert C Green; Arthur W Toga; Michael W Weiner
Journal:  Alzheimers Dement       Date:  2015-07       Impact factor: 21.566

Review 2.  Early Life Stress and Epigenetics in Late-onset Alzheimer's Dementia: A Systematic Review.

Authors:  Erwin Lemche
Journal:  Curr Genomics       Date:  2018-11       Impact factor: 2.236

3.  Exploring Genetic Associations of Alzheimer's Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes.

Authors:  Ana Espinosa; Begoña Hernández-Olasagarre; Sonia Moreno-Grau; Luca Kleineidam; Stefanie Heilmann-Heimbach; Isabel Hernández; Steffen Wolfsgruber; Holger Wagner; Maitée Rosende-Roca; Ana Mauleón; Liliana Vargas; Asunción Lafuente; Octavio Rodríguez-Gómez; Carla Abdelnour; Silvia Gil; Marta Marquié; Miguel A Santos-Santos; Ángela Sanabria; Gemma Ortega; Gemma Monté-Rubio; Alba Pérez; Marta Ibarria; Susana Ruiz; Johannes Kornhuber; Oliver Peters; Lutz Frölich; Michael Hüll; Jens Wiltfang; Tobias Luck; Steffi Riedel-Heller; Laura Montrreal; Pilar Cañabate; Mariola Moreno; Silvia Preckler; Nuria Aguilera; Itziar de Rojas; Adelina Orellana; Montserrat Alegret; Sergi Valero; Markus M Nöthen; Michael Wagner; Frank Jessen; Lluis Tárraga; Mercè Boada; Alfredo Ramírez; Agustín Ruiz
Journal:  Front Aging Neurosci       Date:  2018-10-30       Impact factor: 5.750
  3 in total

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