Literature DB >> 25914909

Hydrogel dressings for treating pressure ulcers.

Jo C Dumville1, Nikki Stubbs, Samantha J Keogh, Rachel M Walker, Zhenmi Liu.   

Abstract

BACKGROUND: Pressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Dressings are widely used to treat pressure ulcers and there are many different dressing options including hydrogel dressings. A clear and current overview of the current evidence is required to facilitate decision-making regarding dressing use for the treatment of pressure ulcers.
OBJECTIVES: To assess the effects of hydrogel dressings on the healing of pressure ulcers in any care setting. SEARCH
METHODS: We searched the following databases: the Cochrane Wounds Group Specialised Register (searched 19 June 2014); The Cochrane Central Register of Controlled Trials (CENTRAL; 2014, Issue 5); Ovid MEDLINE (1946 to June Week 2 2014); Ovid MEDLINE (In-Process & Other Non-Indexed Citations, 23 June 2014); Ovid EMBASE (1974 to 20 June 2014); and EBSCO CINAHL (1982 to 18 June 2014). There were no restrictions based on language or date of publication. SELECTION CRITERIA: Published or unpublished randomised controlled trials (RCTs) comparing the effects of hydrogel dressings with alternative wound dressings or no dressing in the treatment of pressure ulcers (stage II or above). DATA COLLECTION AND ANALYSIS: Two review authors independently performed study selection, risk of bias assessment and data extraction. MAIN
RESULTS: We included eleven studies (523 participants) in this review. Ten studies had two arms and one had three arms that were all relevant to this review. Three studies compared a hydrogel dressing with a basic wound contact dressing; three studies compared a hydrogel dressing with a hydrocolloid dressing; three studies compared a hydrogel dressing with another hydrogel dressing; one study compared a hydrogel dressing with a foam dressing; one study compared a hydrogel dressing with a dextranomer paste dressing and one study compared a hydrogel dressing with a topical treatment (collagenase). Limited data were available for analyses in this review: we conducted no meta-analyses. Where data were available there was no evidence of a difference between hydrogel and alternative treatments in terms of complete wound healing or adverse events. One small study reported that using hydrogel dressings was, on average, less costly than hydrocolloid dressings, but this estimate was imprecise and its methodology was not clear. All included studies were small, had short follow-up times and were at unclear risk of bias. AUTHORS'
CONCLUSIONS: It is not clear if hydrogel dressings are more or less effective than other treatments in healing pressure ulcers or if different hydrogels have different effects, Most trials in this field are very small and poorly reported so that risk of bias is unclear.

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Year:  2015        PMID: 25914909     DOI: 10.1002/14651858.CD011226.pub2

Source DB:  PubMed          Journal:  Cochrane Database Syst Rev        ISSN: 1361-6137


  14 in total

Review 1.  Dressings and topical agents for treating pressure ulcers.

Authors:  Maggie J Westby; Jo C Dumville; Marta O Soares; Nikki Stubbs; Gill Norman
Journal:  Cochrane Database Syst Rev       Date:  2017-06-22

2.  Rigid dressings versus soft dressings for transtibial amputations.

Authors:  Li Khim Kwah; Matthew T Webb; Lina Goh; Lisa A Harvey
Journal:  Cochrane Database Syst Rev       Date:  2019-06-17

3.  Physical properties of hydrogel wound dressing and its use in low-level laser therapy (LLLT).

Authors:  K Wachal; E Stachowska; K Korpuścińska; B Nowak; Z Krasiński
Journal:  Lasers Med Sci       Date:  2018-04-02       Impact factor: 3.161

Review 4.  Review of the Current Management of Pressure Ulcers.

Authors:  Tatiana V Boyko; Michael T Longaker; George P Yang
Journal:  Adv Wound Care (New Rochelle)       Date:  2018-02-01       Impact factor: 4.730

Review 5.  Interventions for pressure ulcers: a summary of evidence for prevention and treatment.

Authors:  Ross A Atkinson; Nicky A Cullum
Journal:  Spinal Cord       Date:  2018-01-25       Impact factor: 2.772

6.  Organisation of health services for preventing and treating pressure ulcers.

Authors:  Pauline Joyce; Zena Eh Moore; Janice Christie
Journal:  Cochrane Database Syst Rev       Date:  2018-12-09

7.  Porcine tri-layer wound matrix for the treatment of stage IV pressure ulcers.

Authors:  Paula J Beers; Cheri N Adgerson; Susan B Millan
Journal:  JAAD Case Rep       Date:  2016-03-04

Review 8.  Topical phenytoin for treating pressure ulcers.

Authors:  Xiang Yong Hao; Hong Ling Li; He Su; Hui Cai; Tian Kang Guo; Ruifeng Liu; Lei Jiang; Yan Fei Shen
Journal:  Cochrane Database Syst Rev       Date:  2017-02-22

Review 9.  Antibiotics and antiseptics for pressure ulcers.

Authors:  Gill Norman; Jo C Dumville; Zena E H Moore; Judith Tanner; Janice Christie; Saori Goto
Journal:  Cochrane Database Syst Rev       Date:  2016-04-04

10.  Support surfaces for treating pressure ulcers.

Authors:  Elizabeth McInnes; Asmara Jammali-Blasi; Sally Em Bell-Syer; Vannessa Leung
Journal:  Cochrane Database Syst Rev       Date:  2018-10-11
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