| Literature DB >> 25914451 |
Michele Orditura1, Gennaro Galizia1, Eva Lieto1, Ferdinando De Vita1, Fortunato Ciardiello1.
Abstract
The incidence of esophagogastric junction adenocarcinoma (AEG) is increasing worldwide. Barrett's esophagus (BE) associated with dysplasia is the main risk factor for the development of cancer. Currently, screening programs to individuate and eradicate BE represent the best way to reduce AEG cancer. Several endoscopic approaches are here discussed. Surgical strategies for different types of AEG cancer are now fairly standardized, and multidisciplinary strategies using chemotherapy or chemoradiotherapy may improve the outcome of these patients. Here we briefly discuss the keypoints, main topics, and critical issues, according to accumulating evidence and taking into account our own experience.Entities:
Keywords: Barrett’s esophagus; Chemoradiotherapy; Chemotherapy; Endoscopic resection; Esophagogastric junction adenocarcinoma; Surgery
Mesh:
Year: 2015 PMID: 25914451 PMCID: PMC4402289 DOI: 10.3748/wjg.v21.i15.4427
Source DB: PubMed Journal: World J Gastroenterol ISSN: 1007-9327 Impact factor: 5.742