| Literature DB >> 25912134 |
Siok Lam Lim1, Carlos J Rodriguez-Ortiz1, Masashi Kitazawa2.
Abstract
Alzheimer's disease (AD) is a leading cause of dementia among elderly. Yet, its etiology remains largely unclear. In this review, we summarize studies that associate systemic infection and neuroinflammation with AD, while highlighting that early-life or life-long exposure to infectious agents predisposes one to develop AD at a later age.Entities:
Keywords: Alzheimer's disease; Environment; Infection; Inflammation; Risk factors; Sporadic
Mesh：
Year: 2015 PMID： 25912134 DOI： 10.1016/j.micinf.2015.04.004
Source DB: PubMed Journal: Microbes Infect ISSN： 1286-4579 Impact factor: 2.700