| Literature DB >> 25910680 |
Zhiyong Di1, Yao Yu2, Yingliang Wu3, Pei Hao4, Yawen He3, Huabin Zhao3, Yixue Li4, Guoping Zhao2, Xuan Li5, Wenxin Li6, Zhijian Cao7.
Abstract
Homeobox genes belong to a large gene group, which encodes the famous DNA-binding homeodomain that plays a key role in development and cellular differentiation during embryogenesis in animals. Here, one hundred forty-nine homeobox genes were identified from the Asian scorpion, Mesobuthus martensii (Chelicerata: Arachnida: Scorpiones: Buthidae) based on our newly assembled genome sequence with approximately 248 × coverage. The identified homeobox genes were categorized into eight classes including 82 families: 67 ANTP class genes, 33 PRD genes, 11 LIM genes, five POU genes, six SINE genes, 14 TALE genes, five CUT genes, two ZF genes and six unclassified genes. Transcriptome data confirmed that more than half of the genes were expressed in adults. The homeobox gene diversity of the eight classes is similar to the previously analyzed Mandibulata arthropods. Interestingly, it is hypothesized that the scorpion M. martensii may have two Hox clusters. The first complete genome-wide analysis of homeobox genes in Chelicerata not only reveals the repertoire of scorpion, arachnid and chelicerate homeobox genes, but also shows some insights into the evolution of arthropod homeobox genes.Entities:
Keywords: Genome-wide analysis; Homeobox genes; Hox cluster; Scorpion
Mesh：
Year: 2015 PMID： 25910680 DOI： 10.1016/j.ibmb.2015.04.002
Source DB: PubMed Journal: Insect Biochem Mol Biol ISSN： 0965-1748 Impact factor: 4.714