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Literature DB >> 25910199

Natural evolution of broadly neutralizing antibodies.

Abstract

Wu et al. couple next-generation sequencing with structural analysis to illuminate the key processes that enable the natural evolution and selection of broadly neutralizing antibodies to HIV-1, providing a potential roadmap for the development of HIV-1 vaccine strategies to accelerate the induction of protective antibodies.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Antibodies, Neutralizing

Year: 2015 PMID： 25910199 PMCID： PMC4426205 DOI： 10.1016/j.cell.2015.04.007

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

6 in total

1. The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection.

Authors: Elin S Gray; Maphuti C Madiga; Tandile Hermanus; Penny L Moore; Constantinos Kurt Wibmer; Nancy L Tumba; Lise Werner; Koleka Mlisana; Sengeziwe Sibeko; Carolyn Williamson; Salim S Abdool Karim; Lynn Morris
Journal: J Virol Date: 2011-03-09 Impact factor: 5.103

2. Breadth of neutralizing antibody response to human immunodeficiency virus type 1 is affected by factors early in infection but does not influence disease progression.

Authors: Anne Piantadosi; Dana Panteleeff; Catherine A Blish; Jared M Baeten; Walter Jaoko; R Scott McClelland; Julie Overbaugh
Journal: J Virol Date: 2009-07-29 Impact factor: 5.103

Review 3. A Blueprint for HIV Vaccine Discovery.

Authors: Dennis R Burton; Rafi Ahmed; Dan H Barouch; Salvatore T Butera; Shane Crotty; Adam Godzik; Daniel E Kaufmann; M Juliana McElrath; Michel C Nussenzweig; Bali Pulendran; Chris N Scanlan; William R Schief; Guido Silvestri; Hendrik Streeck; Bruce D Walker; Laura M Walker; Andrew B Ward; Ian A Wilson; Richard Wyatt
Journal: Cell Host Microbe Date: 2012-10-18 Impact factor: 21.023

4. Characteristics of the earliest cross-neutralizing antibody response to HIV-1.

Authors: Iliyana Mikell; D Noah Sather; Spyros A Kalams; Marcus Altfeld; Galit Alter; Leonidas Stamatatos
Journal: PLoS Pathog Date: 2011-01-13 Impact factor: 6.823

Review 5. Structural insights on the role of antibodies in HIV-1 vaccine and therapy.

Authors: Anthony P West; Louise Scharf; Johannes F Scheid; Florian Klein; Pamela J Bjorkman; Michel C Nussenzweig
Journal: Cell Date: 2014-02-13 Impact factor: 41.582

6. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.

Authors: Hua-Xin Liao; Rebecca Lynch; Tongqing Zhou; Feng Gao; S Munir Alam; Scott D Boyd; Andrew Z Fire; Krishna M Roskin; Chaim A Schramm; Zhenhai Zhang; Jiang Zhu; Lawrence Shapiro; James C Mullikin; S Gnanakaran; Peter Hraber; Kevin Wiehe; Garnett Kelsoe; Guang Yang; Shi-Mao Xia; David C Montefiori; Robert Parks; Krissey E Lloyd; Richard M Scearce; Kelly A Soderberg; Myron Cohen; Gift Kamanga; Mark K Louder; Lillian M Tran; Yue Chen; Fangping Cai; Sheri Chen; Stephanie Moquin; Xiulian Du; M Gordon Joyce; Sanjay Srivatsan; Baoshan Zhang; Anqi Zheng; George M Shaw; Beatrice H Hahn; Thomas B Kepler; Bette T M Korber; Peter D Kwong; John R Mascola; Barton F Haynes
Journal: Nature Date: 2013-04-03 Impact factor: 49.962

6 in total

5 in total

1. Conformational Epitope-Specific Broadly Neutralizing Plasma Antibodies Obtained from an HIV-1 Clade C-Infected Elite Neutralizer Mediate Autologous Virus Escape through Mutations in the V1 Loop.

Authors: Shilpa Patil; Rajesh Kumar; Suprit Deshpande; Sweety Samal; Tripti Shrivastava; Saikat Boliar; Manish Bansal; Nakul Kumar Chaudhary; Aylur K Srikrishnan; Kailapuri G Murugavel; Suniti Solomon; Melissa Simek; Wayne C Koff; Rajat Goyal; Bimal K Chakrabarti; Jayanta Bhattacharya
Journal: J Virol Date: 2016-01-13 Impact factor: 5.103

2. A Respiratory Syncytial Virus Attachment Gene Variant Associated with More Severe Disease in Infants Decreases Fusion Protein Expression, Which May Facilitate Immune Evasion.

Authors: Stacey Human; Anne L Hotard; Larry J Anderson; Tina V Hartert; Martin L Moore; Christina A Rostad; Sujin Lee; Louise McCormick; Emma K Larkin; Teresa C T Peret; Jaume Jorba; Joseph Lanzone; Tebeb Gebretsadik; John V Williams; Melissa Bloodworth; Matthew Stier; Kecia Carroll; R Stokes Peebles
Journal: J Virol Date: 2020-12-22 Impact factor: 5.103