| Literature DB >> 25908571 |
Zhaoli Liang1, Fei Wang1, Pinhong Chen1, Guosheng Liu1.
Abstract
A highly selective and efficient approach for the direct trifluoromethylthiocyanation of alkenes has been developed using trimethylsilyl isothiocyanate (TMSNCS) as the thiocyanating agent and Togni reagent as the CF3 source in the presence of copper(I) catalyst. Both activated and unactivated alkenes work well to deliver various CF3-containing thiocyanates.Entities:
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Year: 2015 PMID： 25908571 DOI： 10.1021/acs.orglett.5b00939
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005