Literature DB >> 25907889

Software solutions for the livestock genomics SNP array revolution.

E L Nicolazzi1, S Biffani2, F Biscarini1, P Orozco Ter Wengel3, A Caprera1, N Nazzicari1, A Stella1,2.   

Abstract

Since the beginning of the genomic era, the number of available single nucleotide polymorphism (SNP) arrays has grown considerably. In the bovine species alone, 11 SNP chips not completely covered by intellectual property are currently available, and the number is growing. Genomic/genotype data are not standardized, and this hampers its exchange and integration. In addition, software used for the analyses of these data usually requires not standard (i.e. case specific) input files which, considering the large amount of data to be handled, require at least some programming skills in their production. In this work, we describe a software toolkit for SNP array data management, imputation, genome-wide association studies, population genetics and genomic selection. However, this toolkit does not solve the critical need for standardization of the genotypic data and software input files. It only highlights the chaotic situation each researcher has to face on a daily basis and gives some helpful advice on the currently available tools in order to navigate the SNP array data complexity.
© 2015 Stichting International Foundation for Animal Genetics.

Entities:  

Keywords:  genome-wide association studies; genomic selection; imputation; livestock species; management; population genetics; single nucleotide polymorphism

Mesh:

Year:  2015        PMID: 25907889     DOI: 10.1111/age.12295

Source DB:  PubMed          Journal:  Anim Genet        ISSN: 0268-9146            Impact factor:   3.169


  8 in total

1.  The Valdostana goat: a genome-wide investigation of the distinctiveness of its selective sweep regions.

Authors:  Andrea Talenti; Francesca Bertolini; Giulio Pagnacco; Fabio Pilla; Paolo Ajmone-Marsan; Max F Rothschild; Paola Crepaldi
Journal:  Mamm Genome       Date:  2017-03-02       Impact factor: 2.957

2.  Assessing single-nucleotide polymorphism selection methods for the development of a low-density panel optimized for imputation in South African Drakensberger beef cattle.

Authors:  Simon F Lashmar; Donagh P Berry; Rian Pierneef; Farai C Muchadeyi; Carina Visser
Journal:  J Anim Sci       Date:  2021-07-01       Impact factor: 3.159

3.  SNPConvert: SNP Array Standardization and Integration in Livestock Species.

Authors:  Ezequiel Luis Nicolazzi; Gabriele Marras; Alessandra Stella
Journal:  Microarrays (Basel)       Date:  2016-06-09

4.  TheSNPpit-A High Performance Database System for Managing Large Scale SNP Data.

Authors:  Eildert Groeneveld; Helmut Lichtenberg
Journal:  PLoS One       Date:  2016-10-25       Impact factor: 3.240

5.  Genome-enabled predictions for fruit weight and quality from repeated records in European peach progenies.

Authors:  Filippo Biscarini; Nelson Nazzicari; Marco Bink; Pere Arús; Maria José Aranzana; Ignazio Verde; Sabrina Micali; Thierry Pascal; Benedicte Quilot-Turion; Patrick Lambert; Cassia da Silva Linge; Igor Pacheco; Daniele Bassi; Alessandra Stella; Laura Rossini
Journal:  BMC Genomics       Date:  2017-06-06       Impact factor: 3.969

6.  Investigating the Features of PDO Green Hams during Salting: Insights for New Markers and Genomic Regions in Commercial Hybrid Pigs.

Authors:  Martina Zappaterra; Paolo Zambonelli; Cristina Schivazappa; Nicoletta Simoncini; Roberta Virgili; Bruno Stefanon; Roberta Davoli
Journal:  Animals (Basel)       Date:  2021-01-01       Impact factor: 2.752

Review 7.  Toward Genome-Based Selection in Asian Seabass: What Can We Learn From Other Food Fishes and Farm Animals?

Authors:  László Orbán; Xueyan Shen; Norman Phua; László Varga
Journal:  Front Genet       Date:  2021-04-21       Impact factor: 4.599

Review 8.  Suitability of GWAS as a Tool to Discover SNPs Associated with Tick Resistance in Cattle: A Review.

Authors:  Nelisiwe Mkize; Azwihangwisi Maiwashe; Kennedy Dzama; Bekezela Dube; Ntanganedzeni Mapholi
Journal:  Pathogens       Date:  2021-12-09
  8 in total

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