| Literature DB >> 25907706 |
Musaddiq Awan1, Stanley Liu, Arjun Sahgal, Sunit Das, Samuel T Chao, Eric L Chang, Jonathan P S Knisely, Kristin Redmond, Jason W Sohn, Mitchell Machtay, Andrew E Sloan, David B Mansur, Lisa R Rogers, Simon S Lo.
Abstract
Extra-CNS metastasis from glioblastoma (ECMGBM) is an emerging but little known clinical entity. We review pre-clinical and translational publications assessing the ability of GBM to spread locally and outside the CNS. Reported cases demonstrating ECMGBM are reviewed providing a summary of presentations for the entity. Special attention is placed on transmission of GBM through organ transplantation. Finally, predictions are made as to the future significance of ECMGBM, especially in the context of better outcomes in CNS GBM.Entities:
Keywords: circulating tumor cells; glioblastoma; gliomas; malignancy in transplant patients; organ transplantation
Mesh：
Year: 2015 PMID： 25907706 DOI： 10.1586/14737140.2015.1028374
Source DB: PubMed Journal: Expert Rev Anticancer Ther ISSN： 1473-7140 Impact factor: 4.512