Literature DB >> 25903778

Cutaneous lymphoma misdiagnosed as chronic lymphadenitis.

Mircea Munteanu1, Georgiana S Mohor2, Flavia Baderca1,3, Caius Solovan1,2.   

Abstract

Cutaneous lymphomas (CLs) represent a group of lymphoproliferative disorders that can be difficult to diagnose in the early stage because they could mimic many benign inflammatory dermatoses (chronic eczema, bullous dermatosis, idiopathic erythroderma, psoriasis, lymphadenitis). Primary cutaneous B-cell lymphomas are a unique and controversial group of skin lymphomas characterised by the absence of extracutaneous manifestations at diagnosis. We present the case of a 60-year-old man with 7-month history of a growing inguinal mass/tumour, which was misdiagnosed as inguinal chronic lymphadenitis. Recognition of the correct entity, primary cutaneous diffuse large B-cell lymphoma leg type, led to an appropriate therapeutic strategy, knowing that these types of tumours behave more aggressively than other types of primary cutaneous B-cell lymphomas. The patient was discharged with rituximab + chemotherapy indication and favourable outcome. The aim of the presentation is to describe these common skin manifestations, however seen in a primary cutaneous B-cell lymphoma, which underlines the necessity of rigorous monitoring/long-term follow-up as well as exhaustive histopathological analysis for the diagnosis.
© 2015 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

Entities:  

Keywords:  B cell; Cutaneous lymphoma; Inflammatory dermatoses; Inguinal wound; Lymphadenitis

Mesh:

Year:  2015        PMID: 25903778      PMCID: PMC7949857          DOI: 10.1111/iwj.12447

Source DB:  PubMed          Journal:  Int Wound J        ISSN: 1742-4801            Impact factor:   3.315


  17 in total

1.  From inflammation to neoplasia: mycosis fungoides evolves from reactive inflammatory conditions (lymphoid infiltrates) transforming into neoplastic plaques and tumors.

Authors:  G Burg; R Dummer; A Haeffner; W Kempf; M Kadin
Journal:  Arch Dermatol       Date:  2001-07

Review 2.  EORTC classification for primary cutaneous lymphomas: a proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer.

Authors:  R Willemze; H Kerl; W Sterry; E Berti; L Cerroni; S Chimenti; J L Diaz-Peréz; M L Geerts; M Goos; R Knobler; E Ralfkiaer; M Santucci; N Smith; J Wechsler; W A van Vloten; C J Meijer
Journal:  Blood       Date:  1997-07-01       Impact factor: 22.113

3.  Primary cutaneous B-cell lymphomas.

Authors:  Werner Kempf; Natalja Denisjuk; Katrin Kerl; Antonio Cozzio; Christian Sander
Journal:  J Dtsch Dermatol Ges       Date:  2012-01       Impact factor: 5.584

4.  Primary cutaneous large B-cell lymphoma, leg type.

Authors:  Vibha Thomas; Robin Dobson; Robert Mennel
Journal:  Proc (Bayl Univ Med Cent)       Date:  2011-10

Review 5.  Epidemiology of lymphomas.

Authors:  Eve Roman; Alexandra G Smith
Journal:  Histopathology       Date:  2011-01       Impact factor: 5.087

Review 6.  Primary cutaneous B-cell lymphomas: recent advances in diagnosis and management.

Authors:  Lubomir Sokol; Mojdeh Naghashpour; L Frank Glass
Journal:  Cancer Control       Date:  2012-07       Impact factor: 3.302

7.  Cutaneous B-cell lymphomas: 2015 update on diagnosis, risk-stratification, and management.

Authors:  Ryan A Wilcox
Journal:  Am J Hematol       Date:  2015-01       Impact factor: 10.047

8.  Primary cutaneous large B-cell lymphomas: clinicopathologic features, classification, and prognostic factors in a large series of patients.

Authors:  Kazuo Kodama; Cesare Massone; Andreas Chott; Dieter Metze; Helmut Kerl; Lorenzo Cerroni
Journal:  Blood       Date:  2005-06-09       Impact factor: 22.113

9.  Lymphogranuloma venereum: biopsy, serology, and molecular biology.

Authors:  D J Kellock; R Barlow; S K Suvarna; S Green; A Eley; K E Rogstad
Journal:  Genitourin Med       Date:  1997-10

10.  Hepatitis C and G viruses in B-cell lymphomas of the skin.

Authors:  Sonja Michaelis; Dmitry V Kazakov; Mirka Schmid; Reinhard Dummer; Günter Burg; Werner Kempf
Journal:  J Cutan Pathol       Date:  2003-07       Impact factor: 1.587

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