Literature DB >> 25903721

Antiretroviral therapy-induced toxicity is associated with increased mRNA expression of telomerase.

Min Li1, Yram Foli1, Nana Y Amakye2, Taline Klein3, Shanmugapriya Selvaraj1, Lingeng Lu4, Elijah Paintsil1,4,5.   

Abstract

Entities:  

Keywords:  antiretroviral therapy; immune activation; mitochondrial toxicity; telomerase; telomere length

Mesh：

Substances：

Year:  2015        PMID： 25903721      PMCID： PMC4558235          DOI： 10.1002/jcph.520

Source DB:  PubMed          Journal:  J Clin Pharmacol        ISSN： 0091-2700            Impact factor:   3.126


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  26 in total

1.  Analysis of telomerase processivity: mechanistic similarity to HIV-1 reverse transcriptase and role in telomere maintenance.

Authors:  Y Peng; I S Mian; N F Lue
Journal:  Mol Cell       Date:  2001-06       Impact factor: 17.970

2.  The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations.

Authors:  Lawrence A Loeb; Douglas C Wallace; George M Martin
Journal:  Proc Natl Acad Sci U S A       Date:  2005-12-19       Impact factor: 11.205

3.  Human normal T lymphocytes and lymphoid cell lines do express alternative splicing variants of human telomerase reverse transcriptase (hTERT) mRNA.

Authors:  Marit Jalink; Zheng Ge; Cheng Liu; Magnus Björkholm; Astrid Gruber; Dawei Xu
Journal:  Biochem Biophys Res Commun       Date:  2006-12-27       Impact factor: 3.575

4.  Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators.

Authors:  F J Palella; K M Delaney; A C Moorman; M O Loveless; J Fuhrer; G A Satten; D J Aschman; S D Holmberg
Journal:  N Engl J Med       Date:  1998-03-26       Impact factor: 91.245

Review 5.  Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity.

Authors:  T N Kakuda
Journal:  Clin Ther       Date:  2000-06       Impact factor: 3.393

6.  Increases in T cell telomere length in HIV infection after antiretroviral combination therapy for HIV-1 infection implicate distinct population dynamics in CD4+ and CD8+ T cells.

Authors:  S Kaushal; A L Landay; M M Lederman; E Connick; J Spritzler; D R Kuritzkes; H Kessler; B L Levine; D C St Louis; C H June
Journal:  Clin Immunol       Date:  1999-07       Impact factor: 3.969

7.  Differentiating alternative splice variant patterns of human telomerase reverse transcriptase in thyroid neoplasms.

Authors:  Yongchun Wang; Jeanne Kowalski; Hua-Ling Tsai; Radharani Marik; Nijaguna Prasad; Helina Somervell; Pang-Kuo Lo; Lauren E Sangenario; Lars Dyrskjot; Torben F Orntoft; William H Westra; Alan K Meeker; James R Eshleman; Christopher B Umbricht; Martha A Zeiger
Journal:  Thyroid       Date:  2008-10       Impact factor: 6.568

8.  Expression of MDR1 in epithelial ovarian cancer and its association with disease progression.

Authors:  Lingeng Lu; Dionyssios Katsaros; Andrew Wiley; Irene A Rigault de la Longrais; Manuela Puopolo; Herbert Yu
Journal:  Oncol Res       Date:  2007       Impact factor: 5.574

9.  Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts.

Authors:  G A Ulaner; J F Hu; T H Vu; L C Giudice; A R Hoffman
Journal:  Cancer Res       Date:  1998-09-15       Impact factor: 12.701

10.  Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer.

Authors:  C-Q Zhu; J-C Cutz; N Liu; D Lau; F A Shepherd; J A Squire; M-S Tsao
Journal:  Br J Cancer       Date:  2006-05-22       Impact factor: 7.640
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  2 in total

1.  The DNA Polymerase Gamma R953C Mutant Is Associated with Antiretroviral Therapy-Induced Mitochondrial Toxicity.

Authors:  Min Li; Andrea C Mislak; Yram Foli; Esinam Agbosu; Vivek Bose; Shreya Bhandari; Michal R Szymanski; Christie K Shumate; Y Whitney Yin; Karen S Anderson; Elijah Paintsil
Journal:  Antimicrob Agents Chemother       Date:  2016-08-22       Impact factor: 5.191

2.  Correlates of telomere length shortening in peripheral leukocytes of HIV-infected individuals and association with leukoaraiosis.

Authors:  Rumi Minami; Soichiro Takahama; Masahiro Yamamoto
Journal:  PLoS One       Date:  2019-06-27       Impact factor: 3.240
  2 in total

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