Literature DB >> 25903715

Long Term Outcomes from CT-guided Indirect Cervical Nerve Root Blocks and their relationship to the MRI findings--A prospective Study.

Susanne Bensler1,2, Reto Sutter3,4, Christian W A Pfirrmann5,6, Cynthia K Peterson7,8.   

Abstract

PURPOSE: To investigate long-term pain reduction and 'improvement' in patients with indirect cervical nerve-root-blocks in comparison to MRI findings.
MATERIAL AND METHODS: One hundred and twelve patients with MRI confirmed cervical radiculopathy and an indirect cervical nerve-root-block were included. Two radiologists independently evaluated the MRI examinations. 12 different MRI abnormalities at the level and side of infiltration were compared to pain relief and 'improvement' at 1-month, 3-months and 1-year post injection.
RESULTS: The proportion of patients reporting clinically relevant 'improvement' was 36.7% at 1-month, 53.9% at 3-months and 68.1% at 1-year. At 1-month post injection, a statistically significantly lower percentage of patients eventually requiring surgery reported improvement and lower NRS change scores compared to those who did not undergo surgery (p = 0.001). Patients with extrusion of the disc were around 4-times more likely to have surgery. At 1-year post-injection the presence of nerve-root compromise was significantly linked to treatment outcome (p = 0.011).
CONCLUSION: Patients with nerve root compression were more likely to report improvement at 1 year. Patients with disc extrusions have less pain relief and are 4 times more likely to go to surgery than patients with disc protrusions. KEY POINTS: • Good long term outcomes after indirect nerve root infiltrations with non-particulate steroids. • The presence of nerve root compression was a predictive finding of 'improvement'. • Significantly less patients subsequently having surgery had lower NRS scores 1-month post injection. • There is less pain relief in patients with disc extrusions. • There are less improvement in patients with modic type I changes.

Entities:  

Keywords:  CT guided; Cervical nerve root block; Indirect; Long term outcome; MRI

Mesh:

Year:  2015        PMID: 25903715     DOI: 10.1007/s00330-015-3758-4

Source DB:  PubMed          Journal:  Eur Radiol        ISSN: 0938-7994            Impact factor:   5.315


  29 in total

Review 1.  Must we discontinue selective cervical nerve root blocks? Report of two cases and review of the literature.

Authors:  Juerg Hodler; Norbert Boos; Martin Schubert
Journal:  Eur Spine J       Date:  2013-01-18       Impact factor: 3.134

2.  Lumbar nerve root injections: a prospective cohort outcomes study comparing age- and gender-matched patients who returned an outcomes-based postal questionnaire with patients who did not return the postal questionnaire.

Authors:  Marco Lechmann; Cynthia K Peterson; Christian W A Pfirrmann; Jürg Hodler
Journal:  Skeletal Radiol       Date:  2013-07-16       Impact factor: 2.199

3.  Comparative effectiveness of cervical transforaminal injections with particulate and nonparticulate corticosteroid preparations for cervical radicular pain.

Authors:  Paul Dreyfuss; Ray Baker; Nikolai Bogduk
Journal:  Pain Med       Date:  2006 May-Jun       Impact factor: 3.750

4.  CT-guided cervical selective nerve root block with a dorsal approach.

Authors:  T Wolter; S Knoeller; A Berlis; C Hader
Journal:  AJNR Am J Neuroradiol       Date:  2010-08-26       Impact factor: 3.825

5.  Outcome of cervical radiculopathy treated with periradicular/epidural corticosteroid injections: a prospective study with independent clinical review.

Authors:  K Bush; S Hillier
Journal:  Eur Spine J       Date:  1996       Impact factor: 3.134

Review 6.  Adverse central nervous system sequelae after selective transforaminal block: the role of corticosteroids.

Authors:  Robert L Tiso; Thomas Cutler; Joseph A Catania; Karen Whalen
Journal:  Spine J       Date:  2004 Jul-Aug       Impact factor: 4.166

7.  Expenditures and health status among adults with back and neck problems.

Authors:  Brook I Martin; Richard A Deyo; Sohail K Mirza; Judith A Turner; Bryan A Comstock; William Hollingworth; Sean D Sullivan
Journal:  JAMA       Date:  2008-02-13       Impact factor: 56.272

8.  Perils of intravascular methylprednisolone injection into the vertebral artery. An animal study.

Authors:  Gbolahan O Okubadejo; Michael R Talcott; Robert E Schmidt; Aseem Sharma; Alpesh A Patel; R Brian Mackey; Anthony H Guarino; Christopher J Moran; K Daniel Riew
Journal:  J Bone Joint Surg Am       Date:  2008-09       Impact factor: 5.284

9.  Incidence of intravascular penetration in transforaminal cervical epidural steroid injections.

Authors:  Michael B Furman; Michael T Giovanniello; Erin M O'Brien
Journal:  Spine (Phila Pa 1976)       Date:  2003-01-01       Impact factor: 3.468

10.  Imaging-guided lumbar facet injections: is there a difference in outcomes between low back pain patients who remember to return a postal questionnaire and those who do not?

Authors:  Stefanie Kremer; Christian W A Pfirrmann; Juerg Hodler; Cynthia K Peterson
Journal:  Insights Imaging       Date:  2012-06-07
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  8 in total

1.  [Periradicular infiltration therapy : Clinical indications, technique and results].

Authors:  B Oder; S Thurnher
Journal:  Radiologe       Date:  2015-10       Impact factor: 0.635

Review 2.  Spine injections: the rationale for CT guidance.

Authors:  Sanja Bogdanovic; Reto Sutter; Veronika Zubler
Journal:  Skeletal Radiol       Date:  2022-09-23       Impact factor: 2.128

3.  Epidural steroid injection-related events requiring hospitalisation or emergency room visits among 52,935 procedures performed at a single centre.

Authors:  Joon Woo Lee; Eugene Lee; Guen Young Lee; Yusuhn Kang; Joong Mo Ahn; Heung Sik Kang
Journal:  Eur Radiol       Date:  2017-07-19       Impact factor: 5.315

4.  Comparison of three CT-guided epidural steroid injection approaches in 104 patients with cervical radicular pain: transforaminal anterolateral, posterolateral, and transfacet indirect.

Authors:  Sylvain Bise; Lionel Pesquer; Mathieu Feldis; Myriam Bou Antoun; Alain Silvestre; Arnaud Hocquelet; Benjamin Dallaudière
Journal:  Skeletal Radiol       Date:  2018-07-22       Impact factor: 2.199

5.  Relationship of specific MRI findings to treatment outcomes in patients receiving transforaminal epidural steroid injections.

Authors:  Marco Lechmann; Andrea Rosskopf; Christine Ehrmann; Reto Sutter; Christian W A Pfirrmann; Cynthia K Peterson
Journal:  Skeletal Radiol       Date:  2016-09-28       Impact factor: 2.199

6.  Particulate versus non-particulate corticosteroids for transforaminal nerve root blocks: Comparison of outcomes in 494 patients with lumbar radiculopathy.

Authors:  Susanne Bensler; Reto Sutter; Christian W A Pfirrmann; Cynthia K Peterson
Journal:  Eur Radiol       Date:  2017-09-11       Impact factor: 5.315

Review 7.  Diagnosis and Treatment of Cervical Spondylotic Radiculopathy Using Selective Nerve Root Block (SNRB): Where are We Now?

Authors:  Dongfang Yang; Lichen Xu; Yutong Hu; Weibing Xu
Journal:  Pain Ther       Date:  2022-02-15

8.  Systemic effects of fluoroscopically guided epidural steroid injection with dexamethasone.

Authors:  Woo Young Kang; Joon Woo Lee; Eugene Lee; Yusuhn Kang; Joong Mo Ahn; Heung Sik Kang
Journal:  Korean J Pain       Date:  2019-07-01
  8 in total

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