Literature DB >> 25902479

Distinct mechanisms of tumor resistance to NK killing: of mice and men.

Drew M Pardoll1.   

Abstract

Tumors cells can release natural killer (NK) cell ligands for activating receptor NKG2D that are thought to inhibit NK cell function. In a recent issue of Science, Deng et al. (2015) show that, unexpectedly, a soluble NKG2D ligand can enhance anti-tumor NK cell activity.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 25902479      PMCID： PMC5598348          DOI： 10.1016/j.immuni.2015.04.007

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  9 in total

1.  Therapy-induced antibodies to MHC class I chain-related protein A antagonize immune suppression and stimulate antitumor cytotoxicity.

Authors:  Masahisa Jinushi; F Stephen Hodi; Glenn Dranoff
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-05       Impact factor: 11.205

2.  The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor.

Authors:  Stephan Gasser; Sandra Orsulic; Eric J Brown; David H Raulet
Journal:  Nature       Date:  2005-07-03       Impact factor: 49.962

3.  Antitumor immunity. A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection.

Authors:  Weiwen Deng; Benjamin G Gowen; Li Zhang; Lin Wang; Stephanie Lau; Alexandre Iannello; Jianfeng Xu; Tihana L Rovis; Na Xiong; David H Raulet
Journal:  Science       Date:  2015-03-05       Impact factor: 47.728

4.  Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation.

Authors:  Veronika Groh; Jennifer Wu; Cassian Yee; Thomas Spies
Journal:  Nature       Date:  2002-10-17       Impact factor: 49.962

5.  MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells.

Authors:  F M Karlhofer; R K Ribaudo; W M Yokoyama
Journal:  Nature       Date:  1992-07-02       Impact factor: 49.962

Review 6.  Natural killer cell immune responses.

Authors:  Wayne M Yokoyama
Journal:  Immunol Res       Date:  2005       Impact factor: 2.829

7.  A novel primary immunodeficiency with specific natural-killer cell deficiency maps to the centromeric region of chromosome 8.

Authors:  Celine Eidenschenk; Jean Dunne; Emmanuelle Jouanguy; Claire Fourlinnie; Laure Gineau; Delphine Bacq; Corrina McMahon; Owen Smith; Jean-Laurent Casanova; Laurent Abel; Conleth Feighery
Journal:  Am J Hum Genet       Date:  2006-02-17       Impact factor: 11.025

Review 8.  Oncogenic stress sensed by the immune system: role of natural killer cell receptors.

Authors:  David H Raulet; Nadia Guerra
Journal:  Nat Rev Immunol       Date:  2009-08       Impact factor: 53.106

Review 9.  DAP10- and DAP12-associated receptors in innate immunity.

Authors:  Lewis L Lanier
Journal:  Immunol Rev       Date:  2009-01       Impact factor: 12.988
  9 in total
  6 in total

1.  Dynamics of the spleen and its significance in a murine H22 orthotopic hepatoma model.

Authors:  Baohua Li; Shu Zhang; Na Huang; Haiyan Chen; Peijun Wang; Jun Li; Yansong Pu; Jun Yang; Zongfang Li
Journal:  Exp Biol Med (Maywood)       Date:  2016-03-16

2.  Antibody targeting soluble NKG2D ligand sMIC refuels and invigorates the endogenous immune system to fight cancer.

Authors:  Jennifer Wu
Journal:  Oncoimmunology       Date:  2015-10-29       Impact factor: 8.110

3.  Extracellular vesicle-mediated communication between hepatocytes and natural killer cells promotes hepatocellular tumorigenesis.

Authors:  Zhijun Liu; Yuyu You; Qiyi Chen; Guobang Li; Wenfeng Pan; Qing Yang; Jiajun Dong; Yi Wu; Jin-Xin Bei; Chaoyun Pan; Fuming Li; Bo Li
Journal:  Mol Ther       Date:  2021-10-01       Impact factor: 11.454

4.  Soluble NKG2D ligands in the ovarian cancer microenvironment are associated with an adverse clinical outcome and decreased memory effector T cells independent of NKG2D downregulation.

Authors:  Maulik Vyas; Silke Reinartz; Nathalie Hoffmann; Katrin S Reiners; Sonja Lieber; Julia M Jansen; Uwe Wagner; Rolf Müller; Elke Pogge von Strandmann
Journal:  Oncoimmunology       Date:  2017-08-21       Impact factor: 8.110

5.  Silencing NKG2D ligand-targeting miRNAs enhances natural killer cell-mediated cytotoxicity in breast cancer.

Authors:  Jiaying Shen; Jie Pan; Chengyong Du; Wengong Si; Minya Yao; Liang Xu; Huilin Zheng; Mingjie Xu; Danni Chen; Shu Wang; Peifen Fu; Weimin Fan
Journal:  Cell Death Dis       Date:  2017-04-06       Impact factor: 8.469

6.  T-cell epitope strength in WAP-T mouse mammary carcinomas is an important determinant in PD1/PD-L1 immune checkpoint blockade therapy.

Authors:  Michael Bruns; Jara Wanger; Udo Schumacher; Wolfgang Deppert
Journal:  Oncotarget       Date:  2016-10-04
  6 in total

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