Literature DB >> 25901237

Thickness of the ligamentum flavum: correlation with age and its asymmetry-an magnetic resonance imaging study.

Vrushali Subhash Kolte1, Seema Khambatta1, Medha Vijay Ambiye1.   

Abstract

STUDY
DESIGN: A retrospective radiological study of the ligamentum flavum (LF).
PURPOSE: This study is an attempt to measure and compare the thickening of the LF on both the sides with the use of magnetic resonance imaging, to investigate if there is a predominant tendency to thicken a specific side and also to determine if a correlation between the thickening of the LF and increasing age exists. OVERVIEW OF LITERATURE: Even though many studies measured the thickness of the LF, very few have compared it on each side, or determined its correlation with age.
METHODS: The thickness of LF was measured at the L3-4, L4-5, L5-S1 levels on both sides using the magnetic resonance images of 200 patients (n=1,200). The sample population was divided into three groups: 21-40 years, 41-60 years, and 61-80 years. The data was analyzed statistically, comparing the thickness of LF on both sides and in various age-groups.
RESULTS: The thickness of the LF was found to increase with age; however, there were several younger instances with thicknesses >4 mm. The mean thickness of the right LF at different spinal levels was measured (L3-L4=3.38±0.94 mm, L4-L5=3.70±1.16 mm, and L5-S1=3.65±1.16 mm) while the mean thickness of the left LF was higher (L3-L4=3.52±0.99 mm, L4-L5=3.84±1.12 mm, and L5-S1=3.78±1.24 mm).
CONCLUSIONS: The LF thickness does not appear to have any side dominance; however, it tends to thicken with increasing age.

Entities:  

Keywords:  Age; Asymmetry; Ligamentum flavum; MRI measurements; Spinal canal stenosis

Year:  2015        PMID: 25901237      PMCID: PMC4404540          DOI: 10.4184/asj.2015.9.2.245

Source DB:  PubMed          Journal:  Asian Spine J        ISSN: 1976-1902


  15 in total

1.  Role of ligamentum flavum in the symptomatology of prolapsed lumbar intervertebral discs.

Authors:  P S Ramani; R H Perry; B E Tomlinson
Journal:  J Neurol Neurosurg Psychiatry       Date:  1975-06       Impact factor: 10.154

2.  The thickness of the ligamentum flavum in relation to age and gender.

Authors:  Alp Alper Safak; Merih Is; Ozdemir Sevinc; Cagatay Barut; Nesrin Eryoruk; Besir Erdogmus; Murat Dosoglu
Journal:  Clin Anat       Date:  2010-01       Impact factor: 2.414

3.  Ligamentum flavum thickness in normal and stenotic lumbar spines.

Authors:  Janan Abbas; Kamal Hamoud; Youssef M Masharawi; Hila May; Ori Hay; Bahaa Medlej; Natan Peled; Israel Hershkovitz
Journal:  Spine (Phila Pa 1976)       Date:  2010-05-20       Impact factor: 3.468

Review 4.  Lumbar spine stenosis: a common cause of back and leg pain.

Authors:  J A Alvarez; R H Hardy
Journal:  Am Fam Physician       Date:  1998-04-15       Impact factor: 3.292

5.  Normal and degenerative posterior spinal structures: MR imaging.

Authors:  N Grenier; H Y Kressel; M L Schiebler; R I Grossman; M K Dalinka
Journal:  Radiology       Date:  1987-11       Impact factor: 11.105

6.  The "thickened" ligamentum flavum: is it buckling or enlargement?

Authors:  F H Chokshi; R M Quencer; W R K Smoker
Journal:  AJNR Am J Neuroradiol       Date:  2010-09-30       Impact factor: 3.825

7.  Pathomechanism of ligamentum flavum hypertrophy: a multidisciplinary investigation based on clinical, biomechanical, histologic, and biologic assessments.

Authors:  Koichi Sairyo; Ashok Biyani; Vijay Goel; Douglas Leaman; Robert Booth; Jean Thomas; Daniel Gehling; Lakshmi Vishnubhotla; Rebecca Long; Nabil Ebraheim
Journal:  Spine (Phila Pa 1976)       Date:  2005-12-01       Impact factor: 3.468

8.  An anatomical study of the human lumbar ligamentum flavum.

Authors:  Eiman M Abdel-Meguid
Journal:  Neurosciences (Riyadh)       Date:  2008-01       Impact factor: 0.906

9.  Measurements of ligamentum flavum thickening at lumbar spine using MRI.

Authors:  Tadanori Sakamaki; Koichi Sairyo; Toshinori Sakai; Tatsuya Tamura; Yuji Okada; Hiroshi Mikami
Journal:  Arch Orthop Trauma Surg       Date:  2009-03-12       Impact factor: 3.067

10.  [Treatment of lumbar stenosis and root pain resulting from simple hypertrophy of lumbar ligamentum flavum].

Authors:  Li-min Liu; Yue-ming Song; Quan Gong
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2003-01
View more
  7 in total

1.  Clinically significant radiographic parameter for thoracic myelopathy caused by ossification of the ligamentum flavum.

Authors:  Byung-Jou Lee; Jin Hoon Park; Sang-Ryong Jeon; Seung-Chul Rhim; Sung Woo Roh
Journal:  Eur Spine J       Date:  2018-09-06       Impact factor: 3.134

2.  Development of an In Vitro 3D Model for Investigating Ligamentum Flavum Hypertrophy.

Authors:  Cheng-Li Lin; Yi-Ting Kuo; Che-Hao Tsao; Yan-Jye Shyong; Shu-Hsien Shih; Ting-Yuan Tu
Journal:  Biol Proced Online       Date:  2020-09-01       Impact factor: 3.244

3.  Dorsal Spinal Ligamentum Flavum Thickening: A Magnetic Resonance Imaging Study.

Authors:  Amarnath Chelladurai; Suhasini Balasubramaniam; Sarenya Preyah Anbazhagan; Sathyan Gnanasihamani; Sukumar Ramaswami
Journal:  Asian Spine J       Date:  2018-02-07

4.  Optimal cut-off points of lumbar pedicle thickness as a morphological parameter to predict lumbar spinal stenosis syndrome: a retrospective study.

Authors:  Sang Joon An; Soo Il Choi; Keum Nae Kang; Syn-Hae Yoon; Young Uk Kim
Journal:  J Pain Res       Date:  2018-09-04       Impact factor: 3.133

5.  MicroRNA transcriptome analysis on hypertrophy of ligamentum flavum in patients with lumbar spinal stenosis.

Authors:  Taiki Mori; Yoshihito Sakai; Mitsunori Kayano; Akio Matsuda; Keisuke Oboki; Kenji Matsumoto; Atsushi Harada; Shumpei Niida; Ken Watanabe
Journal:  Spine Surg Relat Res       Date:  2017-11-27

6.  Histological difference in ligament flavum between degenerative lumbar canal stenosis and non-stenotic group: A prospective, comparative study.

Authors:  Mantu Jain; Mukund Sable; Amit Purushottam Tirpude; Rabi Narayan Sahu; Sudeep Kumar Samanta; Gurudip Das
Journal:  World J Orthop       Date:  2022-09-18

7.  EGF Contributes to Hypertrophy of Human Ligamentum Flavum via the TGF-β1/Smad3 Signaling Pathway.

Authors:  Kaifan Yang; Yanlin Chen; Xin Xiang; Yanling Lin; Chengshuo Fei; Zesen Chen; Zhongming Lai; Yongpeng Yu; Ruiqian Tan; Jiale Dong; Junxiong Zhang; Peng Li; Liang Wang; Zhongmin Zhang
Journal:  Int J Med Sci       Date:  2022-08-29       Impact factor: 3.642

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.