Literature DB >> 25900693

[Pancreatic cancer- a curable disease].

Perparim Limani1, Panagiotis Samaras2, Mickael Lesurtel1, Rolf Graf1, Michelle L DeOliveira1, Henrik Petrowsky1, Pierre-Alain Clavien1.   

Abstract

Pancreatic cancer is the seventh most common cancer in Switzerland associated with a dismal prognosis. Its natural course is fatal with a 3-year survival rate below 3%. Advances in diagnostic tools, tumor staging and multimodal treatment strategies resulted in an improved 5-year survival rate of over 20%. Patients presenting with pancreatic cancer significantly benefit from a multi-disciplinary treatment strategy in an experienced hepato-pancreato-biliary center. Following a comprehensive tumor staging, surgical resection associated with adjuvant chemotherapy is still the only curative therapy option. The role of neoadjuvant chemotherapy is currently investigated in clinical trials. Patients presenting with advanced pancreatic cancer not eligible for curative treatment might benefit from inclusion into innovative clinical trials with novel treatment concepts.

Entities:  

Keywords:  Pankreas-Chirurgie; Pankreaskarzinom; Pankreatoduodenektomie; Whipple Operation; cancer du pancréas; chirurgie pancréatique; duodenopancréatectomie; multimodal treatment; multimodale Therapie; neoadjuvant and adjuvant chemotherapies; neoadjuvante und adjuvante Chemotherapie; néoadjuvante et adjuvante chimiothérapies; pancreatic cancer; pancreatic resection; pancreaticoduodenectomy; traitement multimodal

Mesh:

Year:  2015        PMID: 25900693     DOI: 10.1024/1661-8157/a001990

Source DB:  PubMed          Journal:  Praxis (Bern 1994)        ISSN: 1661-8157


  3 in total

1.  A Cell-Surface Membrane Protein Signature for Glioblastoma.

Authors:  Dhimankrishna Ghosh; Cory C Funk; Juan Caballero; Nameeta Shah; Katherine Rouleau; John C Earls; Liliana Soroceanu; Greg Foltz; Charles S Cobbs; Nathan D Price; Leroy Hood
Journal:  Cell Syst       Date:  2017-03-29       Impact factor: 10.304

2.  Expression of PTEN and KAI1 tumor suppressor genes in pancreatic carcinoma and its association with different pathological factors.

Authors:  Weidong Huang; Jie Yang; Jun Ren; Jianjun Tang
Journal:  Oncol Lett       Date:  2015-11-17       Impact factor: 2.967

3.  DGCR5 is activated by PAX5 and promotes pancreatic cancer via targeting miR-3163/TOP2A and activating Wnt/β-catenin pathway.

Authors:  Shi-Lei Liu; Chen Cai; Zi-Yi Yang; Zi-You Wu; Xiang-Song Wu; Xue-Feng Wang; Ping Dong; Wei Gong
Journal:  Int J Biol Sci       Date:  2021-01-01       Impact factor: 6.580

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.