Literature DB >> 25899804

NLRP3, a Double-edged Sword in Lung Injury Diseases.

Jun-Xu Wu1, Kai-Hu Shi.   

Abstract

Nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) plays a key role in lung injury diseases regulation, and its expression is increased in lung injury diseases. NLRP3 may be a good therapeutic target for lung injury diseases. The molecular mechanisms of NLRP3 in lung injury diseases remain unclear. It is a key to study the potential mechanism of NLRP3 during lung injury diseases, so that to exploit it as a good target for lung injury diseases therapy.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 25899804     DOI： 10.1007/s10753-015-0163-8

Source DB:  PubMed          Journal:  Inflammation        ISSN： 0360-3997            Impact factor:   4.092


  5 in total

1.  Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammation and injury.

Authors:  Jianbo Wu; Zhibo Yan; David E Schwartz; Jingui Yu; Asrar B Malik; Guochang Hu
Journal:  J Immunol       Date:  2013-02-22       Impact factor: 5.422

2.  Critical role for the NLRP3 inflammasome during acute lung injury.

Authors:  Jamison J Grailer; Bethany A Canning; Miriam Kalbitz; Mikel D Haggadone; Rasika M Dhond; Anuska V Andjelkovic; Firas S Zetoune; Peter A Ward
Journal:  J Immunol       Date:  2014-05-02       Impact factor: 5.422

3.  NLRP3 deletion protects from hyperoxia-induced acute lung injury.

Authors:  Jutaro Fukumoto; Itsuko Fukumoto; Prasanna Tamarapu Parthasarathy; Ruan Cox; Bao Huynh; Gurukumar Kollongod Ramanathan; Rajan Babu Venugopal; Diane S Allen-Gipson; Richard F Lockey; Narasaiah Kolliputi
Journal:  Am J Physiol Cell Physiol       Date:  2013-05-01       Impact factor: 4.249

4.  Autophagy in pulmonary macrophages mediates lung inflammatory injury via NLRP3 inflammasome activation during mechanical ventilation.

Authors:  Yang Zhang; Gongjian Liu; Randal O Dull; David E Schwartz; Guochang Hu
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2014-05-16       Impact factor: 5.464

5.  NLRP3 inflammasome activation is essential for paraquat-induced acute lung injury.

Authors:  Zhenning Liu; Hongyu Zhao; Wei Liu; Tiegang Li; Yu Wang; Min Zhao
Journal:  Inflammation       Date:  2015-02       Impact factor: 4.092
  5 in total
  2 in total

1.  Role of NLRP3 Inflammasome in Eosinophilic and Non-eosinophilic Chronic Rhinosinusitis with Nasal Polyps.

Authors:  Hai Lin; Zhipeng Li; Dong Lin; Chunquan Zheng; Weitian Zhang
Journal:  Inflammation       Date:  2016-12       Impact factor: 4.092

2.  Inflammasome in ALS Skeletal Muscle: NLRP3 as a Potential Biomarker.

Authors:  Leticia Moreno-García; Francisco J Miana-Mena; Laura Moreno-Martínez; Miriam de la Torre; Christian Lunetta; Claudia Tarlarini; Pilar Zaragoza; Ana Cristina Calvo; Rosario Osta
Journal:  Int J Mol Sci       Date:  2021-03-03       Impact factor: 5.923
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.