Literature DB >> 25899122

Cinatrins D and E, and virgaricin B, three novel compounds produced by a fungus, Virgaria boninensis FKI-4958.

Takahiro Ishii1,2, Kenichi Nonaka1,2, Akihiro Sugawara1,2, Masato Iwatsuki1,2, Rokuro Masuma1,2, Tomoyasu Hirose1,2, Toshiaki Sunazuka1,2, Satoshi Ōmura1, Kazuro Shiomi1,2.   

Abstract

Two new hydroxycitric acid lactone derivatives named cinatrins D (1) and E (2), and a new γ-lactam, virgaricin B (3), along with a known similar compound, virgaricin (4), were isolated from a fermentation broth of the fungus Virgaria boninensis FKI-4958. The absolute stereo structures of the new compounds were established by a combination of spectroscopic methods and chemical modifications. All three newly discovered compounds possessed weak antibacterial activity.

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Year:  2015        PMID: 25899122     DOI: 10.1038/ja.2015.45

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  6 in total

1.  Virgaricin produced by Virgaria sp. FKI-4860.

Authors:  Takahiro Ishii; Kenichi Nonaka; Masato Iwatsuki; Rokuro Masuma; Satoshi Omura; Kazuro Shiomi
Journal:  J Antibiot (Tokyo)       Date:  2012-01-11       Impact factor: 2.649

2.  Vinigrol, a novel antihypertensive and platelet aggregation inhibitory agent produced by a fungus, Virgaria nigra. I. Taxonomy, fermentation, isolation, physicochemical and biological properties.

Authors:  T Ando; Y Tsurumi; N Ohata; I Uchida; K Yoshida; M Okuhara
Journal:  J Antibiot (Tokyo)       Date:  1988-01       Impact factor: 2.649

3.  Metabolites from endophytes of the medicinal plant Erythrina crista-galli.

Authors:  Daniela Weber; Susana Gorzalczany; Virginia Martino; Cristina Acevedo; Olov Sterner; Timm Anke
Journal:  Z Naturforsch C J Biosci       Date:  2005 May-Jun

4.  Metabolic products of Stemphylium radicinum. IV. Minor products.

Authors:  J F Grove
Journal:  J Chem Soc Perkin 1       Date:  1971

5.  Phenylglycine methyl ester, a useful tool for absolute configuration determination of various chiral carboxylic acids

Authors: 
Journal:  J Org Chem       Date:  2000-01-28       Impact factor: 4.354

6.  Guadinomines, Type III secretion system inhibitors, produced by Streptomyces sp. K01-0509. I: taxonomy, fermentation, isolation and biological properties.

Authors:  Masato Iwatsuki; Ryuji Uchida; Hitomi Yoshijima; Hideaki Ui; Kazuro Shiomi; Atsuko Matsumoto; Yoko Takahashi; Akio Abe; Hiroshi Tomoda; Satoshi Omura
Journal:  J Antibiot (Tokyo)       Date:  2008-04       Impact factor: 2.649

  6 in total
  3 in total

Review 1.  The chemistry and biology of natural ribomimetics and related compounds.

Authors:  Takeshi Tsunoda; Samuel Tanoeyadi; Philip J Proteau; Taifo Mahmud
Journal:  RSC Chem Biol       Date:  2022-04-07

Review 2.  The Novel Compounds with Biological Activity Derived from Soil Fungi in the Past Decade.

Authors:  Danyu Zhang; Shoujie Li; Mohan Fan; Changqi Zhao
Journal:  Drug Des Devel Ther       Date:  2022-10-12       Impact factor: 4.319

3.  Nitrogen-Containing Secondary Metabolites from a Deep-Sea Fungus Aspergillus unguis and Their Anti-Inflammatory Activity.

Authors:  Cao Van Anh; Yeo Dae Yoon; Jong Soon Kang; Hwa-Sun Lee; Chang-Su Heo; Hee Jae Shin
Journal:  Mar Drugs       Date:  2022-03-20       Impact factor: 5.118

  3 in total

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