Literature DB >> 25898224

New strategies for rapid (18)F-radiolabeling of biomolecules for radionuclide-based in vivo imaging.

Jun-Liang Zeng1, Jian Wang2, Jun-An Ma1.   

Abstract

The increasing availability of highly active no-carrier-added [(18)F]-fluoride makes its use in radiolabeling biomolecules attractive. By incorporating "fluorophilic" elements (Si, B, and Al) into biomolecules, recent advances offer mild and rapid (18)F-labeling approaches without HPLC purification at the radiosynthetic stage while maintaining sufficient specific activity. In this Topical Review, we will discuss the most recent strides in the field.

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Year:  2015        PMID： 25898224     DOI： 10.1021/acs.bioconjchem.5b00180

Source DB:  PubMed          Journal:  Bioconjug Chem        ISSN： 1043-1802            Impact factor:   4.774


  4 in total

Review 1.  18 F-Labeling of Sensitive Biomolecules for Positron Emission Tomography.

Authors:  Hema S Krishnan; Longle Ma; Neil Vasdev; Steven H Liang
Journal:  Chemistry       Date:  2017-09-01       Impact factor: 5.236

2.  Development of [18F]AmBF3 Tetrazine for Radiolabeling of Peptides: Preclinical Evaluation and PET Imaging of [18F]AmBF3-PEG7-Tyr3-Octreotide in an AR42J Pancreatic Carcinoma Model.

Authors:  Sofia Otaru; Andreas Paulus; Surachet Imlimthan; Iida Kuurne; Helena Virtanen; Heidi Liljenbäck; Tuula Tolvanen; Tatsiana Auchynnikava; Anne Roivainen; Kerttuli Helariutta; Mirkka Sarparanta; Anu J Airaksinen
Journal:  Bioconjug Chem       Date:  2022-06-16       Impact factor: 6.069

3.  Rhodium-Catalyzed Geminal Oxyfluorination and Oxytrifluoro-Methylation of Diazocarbonyl Compounds.

Authors:  Weiming Yuan; Lars Eriksson; Kálmán J Szabó
Journal:  Angew Chem Int Ed Engl       Date:  2016-05-24       Impact factor: 15.336

4.  State of the Art in Radiolabeling of Antibodies with Common and Uncommon Radiometals for Preclinical and Clinical Immuno-PET.

Authors:  Marion Chomet; Guus A M S van Dongen; Danielle J Vugts
Journal:  Bioconjug Chem       Date:  2021-05-11       Impact factor: 4.774
  4 in total

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