Leyla Sahebi1, Khalil Ansarin1, Seyyedi Maryam1, Amir Monfaredan2, Hamed Sabbgh Jadid3. 1. Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Science, Daneshgah Street, Postal code 51665118, Tabriz, Iran. 2. Department of Hematology, Tabriz branch, Islamic Azad University of Tabriz, Daneshgah Street, Postal code 51665118, Tabriz, Iran. 3. Physical Medicine and Rehabilitation Research Center, Tabriz University of Medical Science Daneshgah Street, Postal code 51665118, Tabriz, Iran.
Abstract
BACKGROUND: Identifying the factors associated with the recurrence of Mycobacterium tuberculosis (MTB) can help in tuberculosis disease prevention and reducing the burden on the health care system. This study was designed to identify the factors associated with recurrence in MTB patients in five border provinces of Iran. METHODS: In a cross-sectional study (2010 to 2012), clinical, economic, and social factors associated with the recurrence of tuberculosis were evaluated. The data were collected by a questionnaire and survey of medical records. Simple and multiple logistic regression analyses were performed using SPSS V.18. RESULTS: A total of 300 patients with an average age of 51.9 years (SD 24.2) were randomly selected. Overall, 7.2% of the patients were diagnosed with a recurrence of tuberculosis. Sixty-four percent (n = 151) of the patients were in a low-income class. The migration from a village to a city (OR = 8.4) and weight loss (OR = 1.5) were significantly associated with an increased chance of recurrence. CONCLUSION: In this study, the selected provinces of Iran had moderate rates of tuberculosis recurrence in comparison to global reports. Further studies on the relationship of both weight loss and the immigration from a village to a city with tuberculosis recurrence are necessary.
BACKGROUND: Identifying the factors associated with the recurrence of Mycobacterium tuberculosis (MTB) can help in tuberculosis disease prevention and reducing the burden on the health care system. This study was designed to identify the factors associated with recurrence in MTBpatients in five border provinces of Iran. METHODS: In a cross-sectional study (2010 to 2012), clinical, economic, and social factors associated with the recurrence of tuberculosis were evaluated. The data were collected by a questionnaire and survey of medical records. Simple and multiple logistic regression analyses were performed using SPSS V.18. RESULTS: A total of 300 patients with an average age of 51.9 years (SD 24.2) were randomly selected. Overall, 7.2% of the patients were diagnosed with a recurrence of tuberculosis. Sixty-four percent (n = 151) of the patients were in a low-income class. The migration from a village to a city (OR = 8.4) and weight loss (OR = 1.5) were significantly associated with an increased chance of recurrence. CONCLUSION: In this study, the selected provinces of Iran had moderate rates of tuberculosis recurrence in comparison to global reports. Further studies on the relationship of both weight loss and the immigration from a village to a city with tuberculosis recurrence are necessary.
Authors: A Thomas; P G Gopi; T Santha; V Chandrasekaran; R Subramani; N Selvakumar; S I Eusuff; K Sadacharam; P R Narayanan Journal: Int J Tuberc Lung Dis Date: 2005-05 Impact factor: 2.373
Authors: R Singla; D Srinath; S Gupta; P Visalakshi; U K Khalid; N Singla; U A Gupta; S K Bharty; D Behera Journal: Int J Tuberc Lung Dis Date: 2009-04 Impact factor: 2.373
Authors: Kelly E Dooley; Ouafae Lahlou; Iraqi Ghali; Janine Knudsen; My Driss Elmessaoudi; Imad Cherkaoui; Rajae El Aouad Journal: BMC Public Health Date: 2011-02-28 Impact factor: 3.295
Authors: Surendra K Sharma; Gaurav Kaushik; Brajesh Jha; Ninoo George; S K Arora; Deepak Gupta; Urvashi Singh; Mahmud Hanif; R P Vashisht Journal: Indian J Med Res Date: 2011-03 Impact factor: 2.375