Literature DB >> 25897277

The deadly ebola threat in the midst of an overwhelming dengue epidemic.

Alwi Muhd Besari1, Siti Suraiya Md Noor2, Yeong Yeh Lee3.   

Abstract

The recent death tolls and morbidities associated with two deadly viral haemorrhagic fevers (VHFs), i.e., Ebola and dengue, are simply shocking. By the end of August 2014, 65 672 people were afflicted with dengue fever (DF) in Malaysia, with 9505 from Kelantan, and there were 128 reported deaths. More astounding are the death tolls associated with Ebola: 3091 deaths from 6574 reported cases so far. It is not difficult to imagine the potential disaster if Ebola spreads beyond Africa. VHFs are characterised by an acute onset of fever, vascular disruption and a rapid progression to shock and death. The revised World Health Organization (WHO) 2012 classification (dengue with and without warning signs and severe dengue) is more clinically relevant and allows more streamlined admission. With good administrative support and public health and governmental efforts, the dengue epidemic in Malaysia is now more contained. However, there should be no laxity with the imminent lethal Ebola threat. Human-to-human transmission is an important mechanism for the spread of Ebola, and this calls for strict precautions regarding contact with any suspected cases. In contrast, the control and elimination of dengue would require successful control of the vectors and their breeding sites.

Entities:  

Keywords:  Ebola; dengue; fever; hemorrhage; virus

Year:  2014        PMID: 25897277      PMCID: PMC4391449     

Source DB:  PubMed          Journal:  Malays J Med Sci        ISSN: 1394-195X


  12 in total

1.  Acute management of dengue shock syndrome: a randomized double-blind comparison of 4 intravenous fluid regimens in the first hour.

Authors:  N T Ngo; X T Cao; R Kneen; B Wills; V M Nguyen; T Q Nguyen; V T Chu; T T Nguyen; J A Simpson; T Solomon; N J White; J Farrar
Journal:  Clin Infect Dis       Date:  2001-01-15       Impact factor: 9.079

Review 2.  Ebola virus pathogenesis: implications for vaccines and therapies.

Authors:  Nancy Sullivan; Zhi-Yong Yang; Gary J Nabel
Journal:  J Virol       Date:  2003-09       Impact factor: 5.103

3.  Using global maps to predict the risk of dengue in Europe.

Authors:  David J Rogers; Jonathan E Suk; Jan C Semenza
Journal:  Acta Trop       Date:  2013-08-21       Impact factor: 3.112

Review 4.  Basic clinical and laboratory features of filoviral hemorrhagic fever.

Authors:  Mark G Kortepeter; Daniel G Bausch; Mike Bray
Journal:  J Infect Dis       Date:  2011-11       Impact factor: 5.226

5.  Ebola then and now.

Authors:  Joel G Breman; Karl M Johnson
Journal:  N Engl J Med       Date:  2014-09-10       Impact factor: 91.245

6.  Bleeding outcome during a dengue outbreak in 2005 in the East-coast region of Peninsular Malaysia: a prospective study.

Authors:  M N Fariz-Safhan; H P Tee; G A Abu Dzarr; S Sapari; Y Y Lee
Journal:  Trop Biomed       Date:  2014-06       Impact factor: 0.623

7.  Ebola hemorrhagic fever in Kikwit, Democratic Republic of the Congo: clinical observations in 103 patients.

Authors:  M A Bwaka; M J Bonnet; P Calain; R Colebunders; A De Roo; Y Guimard; K R Katwiki; K Kibadi; M A Kipasa; K J Kuvula; B B Mapanda; M Massamba; K D Mupapa; J J Muyembe-Tamfum; E Ndaberey; C J Peters; P E Rollin; E Van den Enden; E Van den Enden
Journal:  J Infect Dis       Date:  1999-02       Impact factor: 5.226

Review 8.  Pathogenesis of the viral hemorrhagic fevers.

Authors:  Slobodan Paessler; David H Walker
Journal:  Annu Rev Pathol       Date:  2012-11-01       Impact factor: 23.472

Review 9.  The role of platelets in the pathogenesis of viral hemorrhagic fevers.

Authors:  Juan C Zapata; Dermot Cox; Maria S Salvato
Journal:  PLoS Negl Trop Dis       Date:  2014-06-12

10.  Dengue and other common causes of acute febrile illness in Asia: an active surveillance study in children.

Authors:  Maria Rosario Capeding; Mary Noreen Chua; Sri Rezeki Hadinegoro; Ismail I H M Hussain; Revathy Nallusamy; Punnee Pitisuttithum; Kusnandi Rusmil; Usa Thisyakorn; Stephen J Thomas; Ngoc Huu Tran; Dewa Nyoman Wirawan; In-Kyu Yoon; Alain Bouckenooghe; Yanee Hutagalung; Thelma Laot; Tram Anh Wartel
Journal:  PLoS Negl Trop Dis       Date:  2013-07-25
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