Literature DB >> 25895829

Detection of the plasmid-mediated quinolone resistance determinants in clinical isolates of Acinetobacter baumannii in China.

Haifei Yang1, Lifen Hu2, Yanyan Liu2,3, Ying Ye1,2,3, Jiabin Li1,2,3,4.   

Abstract

We examined the prevalence of plasmid-mediated quinolone resistance (PMQR) determinants among Acinetobacter baumannii in Anhui, China. And β-lactamase genes and mutations in quinolone resistance-determining regions (QRDRs) were also investigated among the PMQR-positive isolates. Among the 39 A. baumannii isolates, 3 (7.7%) isolates harbored qnrB and 1 (2.6%) harbored qnrS. Mutations in the QRDRs of gyrA were identified in 2 isolates amongst the 4 PMQR-positive isolates. Quinolone resistance could be transferred by conjugation from all 4 PMQR-positive donors. In conclusion, more attention should be taken to prevent the transmission of PMQR genes among A. baumannii.

Entities:  

Keywords:  Acinetobacter baumannii; PMQR; QRDRs; QnrB; QnrS

Mesh：

Substances：

Year:  2016        PMID： 25895829     DOI： 10.1179/1973947815Y.0000000017

Source DB:  PubMed          Journal:  J Chemother        ISSN： 1120-009X            Impact factor:   1.714


  10 in total

Review 1.  Plasmid-mediated quinolone resistance in Enterobacteriaceae: a systematic review with a focus on Mediterranean countries.

Authors:  B Yanat; J-M Rodríguez-Martínez; A Touati
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2016-11-26       Impact factor: 3.267

Review 2.  Multidrug Resistant Acinetobacter baumannii: Resistance by Any Other Name Would Still be Hard to Treat.

Authors:  David A Butler; Mark Biagi; Xing Tan; Samah Qasmieh; Zackery P Bulman; Eric Wenzler
Journal:  Curr Infect Dis Rep       Date:  2019-11-16       Impact factor: 3.725

3.  Molecular and genetic characterization of emerging carbapenemase-producing Acinetobacter baumannii strains from patients and hospital environments in Bangladesh.

Authors:  Refath Farzana; Göte Swedberg; Christian G Giske; Badrul Hasan
Journal:  Infect Prev Pract       Date:  2022-04-27

Review 4.  Acinetobacter spp. as nosocomial pathogens: Epidemiology and resistance features.

Authors:  Saad B Almasaudi
Journal:  Saudi J Biol Sci       Date:  2016-02-11       Impact factor: 4.219

5.  Multiple mechanisms contributing to ciprofloxacin resistance among Gram negative bacteria causing infections to cancer patients.

Authors:  Samira M Hamed; Walid F Elkhatib; Hadir A El-Mahallawy; Mai M Helmy; Mohamed S Ashour; Khaled M A Aboshanab
Journal:  Sci Rep       Date:  2018-08-16       Impact factor: 4.379

Review 6.  Insight into Acinetobacter baumannii: pathogenesis, global resistance, mechanisms of resistance, treatment options, and alternative modalities.

Authors:  Muhammad Asif; Iqbal Ahmad Alvi; Shafiq Ur Rehman
Journal:  Infect Drug Resist       Date:  2018-08-21       Impact factor: 4.003

7.  Impact of target site mutations and plasmid associated resistance genes acquisition on resistance of Acinetobacter baumannii to fluoroquinolones.

Authors:  Mostafa Ahmed Mohammed; Mohammed T A Salim; Bahaa E Anwer; Khaled M Aboshanab; Mohammad M Aboulwafa
Journal:  Sci Rep       Date:  2021-10-11       Impact factor: 4.379

8.  Plasmid-Mediated Fluoroquinolone Resistance in Pseudomonas aeruginosa and Acinetobacter baumannii.

Authors:  Geetha P Venkataramana; Aishwarya K V Lalitha; Shanthi Mariappan; Uma Sekar
Journal:  J Lab Physicians       Date:  2022-02-09

9.  Outcomes and prognostic factors of tigecycline treatment for hospital-acquired pneumonia involving multidrug-resistant Acinetobacter baumannii.

Authors:  Ben Liu; Sha Li; Hai-Tao Li; Xiaokai Wang; Hong-Yi Tan; Shuai Liu; Pin-Hua Pan; Xiao-Gang Li; Xiang-Min Li
Journal:  J Int Med Res       Date:  2020-04       Impact factor: 1.671

10.  Antimicrobial Resistance in Nosocomial Isolates of Gram-Negative Bacteria: Public Health Implications in the Latvian Context.

Authors:  Nityanand Jain; Inese Jansone; Tatjana Obidenova; Raimonds Simanis; Jānis Meisters; Dagnija Straupmane; Aigars Reinis
Journal:  Antibiotics (Basel)       Date:  2021-06-29
  10 in total

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