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Literature DB >> 25895817

IBD. Regulatory T cells for treatment of Crohn's disease.

Abstract

The suppression of excessive immune responses by infusion of regulatory T cells would require a product of high purity, adequate ex vivo expansion and functional stability. A description of the process to obtain an autologous cell product fulfilling these characteristics paves the way to develop clinical trials in humans.

Entities: Disease Species

Mesh：

Year: 2015 PMID： 25895817 DOI： 10.1038/nrgastro.2015.68

Source DB: PubMed Journal: Nat Rev Gastroenterol Hepatol ISSN： 1759-5045 Impact factor: 46.802

10 in total

1. Interleukin-2 and regulatory T cells in graft-versus-host disease.

Authors: John Koreth; Ken-ichi Matsuoka; Haesook T Kim; Sean M McDonough; Bhavjot Bindra; Edwin P Alyea; Philippe Armand; Corey Cutler; Vincent T Ho; Nathaniel S Treister; Don C Bienfang; Sashank Prasad; Dmitrios Tzachanis; Robin M Joyce; David E Avigan; Joseph H Antin; Jerome Ritz; Robert J Soiffer
Journal: N Engl J Med Date: 2011-12-01 Impact factor: 91.245

Review 2. The importance of regulatory T-cell heterogeneity in maintaining self-tolerance.

Authors: Xiaomei Yuan; Guoyan Cheng; Thomas R Malek
Journal: Immunol Rev Date: 2014-05 Impact factor: 12.988

Review 3. Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease.

Authors: Shimon Sakaguchi; Masahiro Ono; Ruka Setoguchi; Haruhiko Yagi; Shohei Hori; Zoltan Fehervari; Jun Shimizu; Takeshi Takahashi; Takashi Nomura
Journal: Immunol Rev Date: 2006-08 Impact factor: 12.988

4. Safety and efficacy of antigen-specific regulatory T-cell therapy for patients with refractory Crohn's disease.

Authors: Pierre Desreumaux; Arnaud Foussat; Matthieu Allez; Laurent Beaugerie; Xavier Hébuterne; Yoram Bouhnik; Maria Nachury; Valérie Brun; Hervé Bastian; Nathalie Belmonte; Michel Ticchioni; Agnès Duchange; Patricia Morel-Mandrino; Virginie Neveu; Nathalie Clerget-Chossat; Miguel Forte; Jean-Frédéric Colombel
Journal: Gastroenterology Date: 2012-08-08 Impact factor: 22.682

5. Low-dose interleukin-2 therapy restores regulatory T cell homeostasis in patients with chronic graft-versus-host disease.

Authors: Ken-ichi Matsuoka; John Koreth; Haesook T Kim; Gregory Bascug; Sean McDonough; Yutaka Kawano; Kazuyuki Murase; Corey Cutler; Vincent T Ho; Edwin P Alyea; Philippe Armand; Bruce R Blazar; Joseph H Antin; Robert J Soiffer; Jerome Ritz
Journal: Sci Transl Med Date: 2013-04-03 Impact factor: 17.956

6. Therapy of type 1 diabetes with CD4(+)CD25(high)CD127-regulatory T cells prolongs survival of pancreatic islets - results of one year follow-up.

Authors: Natalia Marek-Trzonkowska; Małgorzata Myśliwiec; Anita Dobyszuk; Marcelina Grabowska; Ilona Derkowska; Jolanta Juścińska; Radosław Owczuk; Agnieszka Szadkowska; Piotr Witkowski; Wojciech Młynarski; Przemysława Jarosz-Chobot; Artur Bossowski; Janusz Siebert; Piotr Trzonkowski
Journal: Clin Immunol Date: 2014-04-01 Impact factor: 3.969

7. First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127- T regulatory cells.

Authors: Piotr Trzonkowski; Maria Bieniaszewska; Jolanta Juścińska; Anita Dobyszuk; Adam Krzystyniak; Natalia Marek; Jolanta Myśliwska; Andrzej Hellmann
Journal: Clin Immunol Date: 2009-06-25 Impact factor: 3.969

Review 8. Regulatory T cells and their roles in immune dysregulation and allergy.

Authors: Laurence Pellerin; Jennifer A Jenks; Philippe Bégin; Rosa Bacchetta; Kari C Nadeau
Journal: Immunol Res Date: 2014-05 Impact factor: 2.829

9. Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease.

Authors: James B Canavan; Cristiano Scottà; Anna Vossenkämper; Rimma Goldberg; Matthew J Elder; Irit Shoval; Ellen Marks; Emilie Stolarczyk; Jonathan W Lo; Nick Powell; Henrieta Fazekasova; Peter M Irving; Jeremy D Sanderson; Jane K Howard; Simcha Yagel; Behdad Afzali; Thomas T MacDonald; Maria P Hernandez-Fuentes; Nahum Y Shpigel; Giovanna Lombardi; Graham M Lord
Journal: Gut Date: 2015-02-24 Impact factor: 23.059

10. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors: Luke Jostins; Stephan Ripke; Rinse K Weersma; Richard H Duerr; Dermot P McGovern; Ken Y Hui; James C Lee; L Philip Schumm; Yashoda Sharma; Carl A Anderson; Jonah Essers; Mitja Mitrovic; Kaida Ning; Isabelle Cleynen; Emilie Theatre; Sarah L Spain; Soumya Raychaudhuri; Philippe Goyette; Zhi Wei; Clara Abraham; Jean-Paul Achkar; Tariq Ahmad; Leila Amininejad; Ashwin N Ananthakrishnan; Vibeke Andersen; Jane M Andrews; Leonard Baidoo; Tobias Balschun; Peter A Bampton; Alain Bitton; Gabrielle Boucher; Stephan Brand; Carsten Büning; Ariella Cohain; Sven Cichon; Mauro D'Amato; Dirk De Jong; Kathy L Devaney; Marla Dubinsky; Cathryn Edwards; David Ellinghaus; Lynnette R Ferguson; Denis Franchimont; Karin Fransen; Richard Gearry; Michel Georges; Christian Gieger; Jürgen Glas; Talin Haritunians; Ailsa Hart; Chris Hawkey; Matija Hedl; Xinli Hu; Tom H Karlsen; Limas Kupcinskas; Subra Kugathasan; Anna Latiano; Debby Laukens; Ian C Lawrance; Charlie W Lees; Edouard Louis; Gillian Mahy; John Mansfield; Angharad R Morgan; Craig Mowat; William Newman; Orazio Palmieri; Cyriel Y Ponsioen; Uros Potocnik; Natalie J Prescott; Miguel Regueiro; Jerome I Rotter; Richard K Russell; Jeremy D Sanderson; Miquel Sans; Jack Satsangi; Stefan Schreiber; Lisa A Simms; Jurgita Sventoraityte; Stephan R Targan; Kent D Taylor; Mark Tremelling; Hein W Verspaget; Martine De Vos; Cisca Wijmenga; David C Wilson; Juliane Winkelmann; Ramnik J Xavier; Sebastian Zeissig; Bin Zhang; Clarence K Zhang; Hongyu Zhao; Mark S Silverberg; Vito Annese; Hakon Hakonarson; Steven R Brant; Graham Radford-Smith; Christopher G Mathew; John D Rioux; Eric E Schadt; Mark J Daly; Andre Franke; Miles Parkes; Severine Vermeire; Jeffrey C Barrett; Judy H Cho
Journal: Nature Date: 2012-11-01 Impact factor: 49.962

10 in total

3 in total

Review 1. Chromatin Remodeling Protein SMAR1 Is a Critical Regulator of T Helper Cell Differentiation and Inflammatory Diseases.

Authors: Bhalchandra Mirlekar; Dipendra Gautam; Samit Chattopadhyay
Journal: Front Immunol Date: 2017-02-09 Impact factor: 7.561

2. Identification of 14-dehydroergosterol as a novel anti-inflammatory compound inducing tolerogenic dendritic cells.

Authors: Yasuhisa Ano; Kumiko Ikado; Kazutoshi Shindo; Hideki Koizumi; Daisuke Fujiwara
Journal: Sci Rep Date: 2017-10-24 Impact factor: 4.379

Review 3. The Immune System in Transfusion-Related Acute Lung Injury Prevention and Therapy: Update and Perspective.

Authors: Kai Guo; Shuxuan Ma
Journal: Front Mol Biosci Date: 2021-03-24

3 in total