Literature DB >> 25894364

Recent developments in utility of green multi-component reactions for the efficient synthesis of polysubstituted pyrans, thiopyrans, pyridines, and pyrazoles.

Mohamed Hilmy Elnagdi1, Moustafa Sherief Moustafa, Saleh Mohammed Al-Mousawi, Ramadan Ahmed Mekheimer, Kamal Usef Sadek.   

Abstract

Developments made since 2010 in the utilization of multi-component reactions as green efficient methodologies for the synthesis of polysubstituted pyrans, thiopyrans, pyridines, and pyrazoles are reviewed and the mechanisms of these processes are discussed. Reference is made to classical older synthetic methods developed earlier in our laboratories.

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Year:  2015        PMID: 25894364     DOI: 10.1007/s11030-015-9594-2

Source DB:  PubMed          Journal:  Mol Divers        ISSN: 1381-1991            Impact factor:   2.943


  27 in total

1.  Recent strategies for the synthesis of pyridine derivatives.

Authors:  Matthew D Hill
Journal:  Chemistry       Date:  2010-10-25       Impact factor: 5.236

2.  Synthesis and molluscicidal activity of some 1,3,4-triaryl-5-chloropyrazole, pyrano[2,3-c]pyrazole, pyrazolylphthalazine and pyrano[2,3-d]thiazole derivatives.

Authors:  Fathy M Abdelrazek; Farid A Michael; Alaa E Mohamed
Journal:  Arch Pharm (Weinheim)       Date:  2006-06       Impact factor: 3.751

3.  Design, synthesis and evaluation of anticonvulsant activity of pyridinyl-pyrrolidones: a pharmacophore hybrid approach.

Authors:  Nadeem Siddiqui; Waquar Ahsan; M Shamsher Alam; Ruhi Ali; Kamna Srivastava
Journal:  Arch Pharm (Weinheim)       Date:  2011-10-14       Impact factor: 3.751

4.  Green chemistry: a facile synthesis of polyfunctionally substituted thieno[3,4-c]pyridinones and thieno[3,4-d]pyridazinones under neat reaction conditions.

Authors:  Khadijah M Al-Zaydi; Rita M Borik; Ramadan A Mekheimer; Mohamed H Elnagdi
Journal:  Ultrason Sonochem       Date:  2009-12-11       Impact factor: 7.491

5.  Tuning of chemo- and regioselectivities in multicomponent condensations of 5-aminopyrazoles, dimedone, and aldehydes.

Authors:  Valentin A Chebanov; Vyacheslav E Saraev; Sergey M Desenko; Vitaliy N Chernenko; Irina V Knyazeva; Ulrich Groth; Toma N Glasnov; C Oliver Kappe
Journal:  J Org Chem       Date:  2008-05-31       Impact factor: 4.354

6.  Ionic liquid promoted preparation of 4H-thiopyran and pyrimidine nucleoside-thiopyran hybrids through one-pot multi-component reaction of thioamide.

Authors:  Xinying Zhang; Xiaoyan Li; Xuesen Fan; Xia Wang; Dongfang Li; Guirong Qu; Jianji Wang
Journal:  Mol Divers       Date:  2008-12-09       Impact factor: 2.943

7.  A convenient ultrasound-promoted regioselective synthesis of fused polycyclic 4-aryl-3-methyl-4,7-dihydro-1H-pyrazolo[3,4-b]pyridines.

Authors:  Mohammad Nikpassand; Manouchehr Mamaghani; Farhad Shirini; Khalil Tabatabaeian
Journal:  Ultrason Sonochem       Date:  2009-08-07       Impact factor: 7.491

8.  Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating.

Authors:  Kamal Usef Sadek; Ramadan Ahmed Mekheimer; Tahany Mahmoud Mohamed; Moustafa Sherief Moustafa; Mohamed Hilmy Elnagdi
Journal:  Beilstein J Org Chem       Date:  2012-01-04       Impact factor: 2.883

9.  Organocatalysis in synthesis: L-proline as an enantioselective catalyst in the synthesis of pyrans and thiopyrans.

Authors:  Noha M Hilmy Elnagdi; Noura Saad Al-Hokbany
Journal:  Molecules       Date:  2012-04-10       Impact factor: 4.411

10.  Green one pot solvent-free synthesis of pyrano[2,3-c]-pyrazoles and pyrazolo[1,5-a]pyrimidines.

Authors:  Hamad M Al-Matar; Khaled D Khalil; Aisha Y Adam; Mohamed H Elnagdi
Journal:  Molecules       Date:  2010-09-20       Impact factor: 4.411

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  2 in total

Review 1.  Synergy Effects in the Chemical Synthesis and Extensions of Multicomponent Reactions (MCRs)-The Low Energy Way to Ultra-Short Syntheses of Tailor-Made Molecules.

Authors:  Heiner Eckert
Journal:  Molecules       Date:  2017-02-25       Impact factor: 4.411

2.  Facile Three-Component Synthesis, Insecticidal and Antifungal Evaluation of Novel Dihydropyridine Derivatives.

Authors:  Guan-Zhou Yang; Xiao-Fei Shang; Pi-Le Cheng; Xiao-Dan Yin; Jia-Kai Zhu; Ying-Qian Liu; Jing Zhang; Zhi-Jun Zhang
Journal:  Molecules       Date:  2018-09-21       Impact factor: 4.411

  2 in total

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