| Literature DB >> 25893894 |
Christian A Malapit1, Sampada M Chitale1, Meena S Thakur1, Rosa Taboada1, Amy R Howell1.
Abstract
A novel Pt-catalyzed rearrangement of oxaspirohexanes to 3-methylenetetrahydrofurans is reported. Mechanistic studies by (13)C-labeling experiments confirm oxidative addition of Pt(II) regioselectively to the least substituted carbon-carbon bond of the cyclopropane to form a platinacyclobutane intermediate. To our knowledge, this is the first alkoxy-substituted platinacyclobutane that has been observed spectroscopically. The scope and a proposed mechanism of this new Pt-catalyzed transformation are described.Entities:
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Year: 2015 PMID： 25893894 DOI： 10.1021/acs.joc.5b00604
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354