Literature DB >> 25892597

Even modest hypoalbuminemia affects outcomes of colorectal surgery patients.

Zhobin Moghadamyeghaneh1, Grace Hwang1, Mark H Hanna1, Michael J Phelan2, Joseph C Carmichael1, Steven D Mills1, Alessio Pigazzi1, Matthew O Dolich1, Michael J Stamos3.   

Abstract

BACKGROUND: A small decrease in the serum albumin from the normal level is a common condition in preoperative laboratory tests of colorectal surgery patients; however, there is limited data examining these patients. We sought to identify outcomes of such patients.
METHODS: The National Surgical Quality Improvement Program database was used to evaluate all patients who had modest levels of hypoalbuminemia (3 ≤ serum albumin < 3.5 g/dL) before colorectal resection from 2005 to 2012. Multivariate analysis using logistic regression was performed to quantify complications associated with modest hypoalbuminemia.
RESULTS: A total of 108,898 patients undergoing colorectal resection were identified, of which 16,962 (15.6%) had modest levels of preoperative hypoalbuminemia. Postsurgical complications significantly associated (P < .05) with modest hypoalbuminemia were as follows: hospitalization more than 30 days (adjusted odds ratio [AOR], 1.77), deep vein thrombosis (AOR, 1.64), unplanned intubation (AOR, 1.42), ventilator dependency for more than 48 hours (AOR, 1.30), and wound disruption (AOR, 1.22).
CONCLUSIONS: Modest hypoalbuminemia is a common preoperative condition in patients undergoing colorectal resection. Our analysis demonstrates that modest hypoalbuminemia has associations with increased postoperative complications, especially pulmonary complications.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Colorectal surgery; Hypoalbuminemia; Surgical complications

Mesh:

Year:  2015        PMID: 25892597     DOI: 10.1016/j.amjsurg.2014.12.038

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  18 in total

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Review 4.  Implications of preoperative hypoalbuminemia in colorectal surgery.

Authors:  Adam Truong; Mark H Hanna; Zhobin Moghadamyeghaneh; Michael J Stamos
Journal:  World J Gastrointest Surg       Date:  2016-05-27

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