Literature DB >> 25892400

Presence of Hepatitis E Virus in a RED Deer (Cervus elaphus) Population in Central Italy.

I Di Bartolo1, E Ponterio1, G Angeloni1, F Morandi2, F Ostanello3, S Nicoloso4, F M Ruggeri1.   

Abstract

Hepatitis E is an acute human disease caused by the hepatitis E virus (HEV). In addition to humans, HEV has been detected in several animal species and is recognized as a zoonotic pathogen. Pigs, wild boar and deer can be reservoir. In this study, we evaluated HEV prevalence in a free-living red deer (Cervus elaphus) population in central Italy by detecting virus-specific antibodies and RNA in sera. A total of 35 of 251 red deer sera were positive for anti-HEV IgG. HEV RNA was detected in 10 of 91 sera examined. Two genomic fragments targeted by diagnostic PCRs in the capsid region were sequenced, both matching with genotype 3 HEV. Overall results confirmed the occurrence of HEV infection in deer also in Italy.
© 2015 Blackwell Verlag GmbH.

Entities:  

Keywords:  Zoonoses; anti-HEV IgG; genotype 3; hepatitis E; red deer

Mesh：

Substances：

Year:  2015        PMID： 25892400     DOI： 10.1111/tbed.12353

Source DB:  PubMed          Journal:  Transbound Emerg Dis        ISSN： 1865-1674            Impact factor:   5.005


  15 in total

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