Literature DB >> 25892161

Orbital decompression for the management of thyroid eye disease: An analysis of outcomes and complications.

Todd T Kingdom1, Brett W Davies2, Vikram D Durairaj3.   

Abstract

OBJECTIVES/HYPOTHESIS: To analyze the clinical outcomes for a large cohort of patients who underwent orbital decompression for thyroid eye disease (TED) utilizing a consistent surgical approach performed by a single surgical team. STUDY
DESIGN: Retrospective case series.
METHODS: Clinical data were gathered for patients who had undergone surgical decompression for TED. Outcomes analysis included reduction in proptosis (millimeters, Hertel measurements), visual acuity change (Snellen chart), diplopia (new or worsening), and complications.
RESULTS: All patients underwent a combined endoscopic transnasal (medial) and transconjunctival (inferior/lateral) approach. A total of 114 surgeries (orbits) were performed on 77 patients during the period 2002 to 2013. Average follow-up was 31.3 months (range, 1-126 months). At last follow up, mean reduction in proptosis across all patients was 3.2 mm (range, 0-9 mm). Postoperatively, no patients reported new diplopia, whereas two patients reported worsening of their existing diplopia (3.8%). Decompression was performed for proptosis in 62 patients (91 orbits), and for compressive optic neuropathy (CON) in 15 patients (23 orbits). When performed for proptosis, mean reduction in proptosis was 3.4 mm. Vision was maintained or improved in all patients, including those presenting with CON.
CONCLUSIONS: Analysis of outcomes in this large cohort showed no new cases of diplopia and only two cases of worsening diplopia balanced with a mean reduction in proptosis consistent with previously reported series. In addition, we demonstrate excellent results stratified by clinical indication (proptosis vs. CON). These results validate the combined endoscopic-transconjunctival approach to orbital decompression for patients with symptomatic TED. LEVEL OF EVIDENCE: 4.
© 2015 The American Laryngological, Rhinological and Otological Society, Inc.

Entities:  

Keywords:  Thyroid eye disease; decompression; diplopia; orbit; proptosis

Mesh:

Year:  2015        PMID: 25892161     DOI: 10.1002/lary.25320

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  14 in total

Review 1.  Orbital wall decompression in the management of Graves' orbitopathy: a systematic review with meta-analysis.

Authors:  Federico Maria Gioacchini; Shaniko Kaleci; Ettore Cassandro; Alfonso Scarpa; Michele Tulli; Claudia Cassandro; Massimo Ralli; Massimo Re
Journal:  Eur Arch Otorhinolaryngol       Date:  2021-02-18       Impact factor: 2.503

Review 2.  Orbital Decompression for Thyroid Eye Disease.

Authors:  Tara L Braun; Mohin A Bhadkamkar; Kevin T Jubbal; Adam C Weber; Douglas P Marx
Journal:  Semin Plast Surg       Date:  2017-02       Impact factor: 2.314

Review 3.  [Possible surgical approaches to the orbit].

Authors:  H-J Welkoborsky; S K Plontke
Journal:  HNO       Date:  2018-11       Impact factor: 1.284

4.  Preoperative clinical features of reactivated of Graves' orbitopathy after orbital decompression.

Authors:  Y J Woo; J W Kim; J S Yoon
Journal:  Eye (Lond)       Date:  2017-01-06       Impact factor: 3.775

5.  Outcomes of endoscopic orbital decompression for graves' ophthalmopathy.

Authors:  Robbie S R Woods; Qistina Pilson; Natallia Kharytaniuk; Lorraine Cassidy; Rizwana Khan; Conrad V I Timon
Journal:  Ir J Med Sci       Date:  2019-06-16       Impact factor: 1.568

6.  Endoscopic orbital decompression for proptosis in non-thyroid eye disease.

Authors:  Valerie Juniat; J Anthony McGilligan; David Curragh; Dinesh Selva; Saul Rajak
Journal:  Oral Maxillofac Surg       Date:  2019-12-19

Review 7.  Orbital decompression for thyroid eye disease: methods, outcomes, and complications.

Authors:  J M Jefferis; R K Jones; Z I Currie; J H Tan; S M Salvi
Journal:  Eye (Lond)       Date:  2017-12-15       Impact factor: 3.775

8.  The influence of orbital decompression on objective nasal function in patients with graves' orbitopathy.

Authors:  Kerstin Stähr; Laura Holtmann; Anke Schlüter; Friederike Kaster; Michael Oeverhaus; Stephan Lang; Anja Eckstein; Stefan Mattheis
Journal:  Eur Arch Otorhinolaryngol       Date:  2018-08-30       Impact factor: 2.503

Review 9.  Multidisciplinary approach to orbital decompression. A review.

Authors:  Claudio Parrilla; Dario Antonio Mele; Silvia Gelli; Lorenzo Zelano; Francesco Bussu; Mario Rigante; Gustavo Savino; Emanuele Scarano
Journal:  Acta Otorhinolaryngol Ital       Date:  2021-04       Impact factor: 2.124

10.  Tocilizumab for thyroid eye disease.

Authors:  Shirin Hamed Azzam; Swan Kang; Mario Salvi; Daniel G Ezra
Journal:  Cochrane Database Syst Rev       Date:  2018-11-27
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