Literature DB >> 25892151

Improving work outcomes of dysthymia (persistent depressive disorder) in an employed population.

David A Adler1, Debra Lerner2, Zachary L Visco3, Annabel Greenhill4, Hong Chang5, Elina Cymerman6, Francisca Azocar7, William H Rogers8.   

Abstract

OBJECTIVE: To test the effectiveness of a work-focused intervention (WFI) on the work outcomes of employed adults with dysthymia.
METHOD: This subgroup analysis from a randomized controlled trial compares an initial sample of 167 employees (age: ≥45 years), screened for dysthymia using the PC-SAD without current major depressive disorder randomized to WFI (n=85) or usual care (UC) (n=82). Study sites included 19 employers and five additional organizations. Telephone-based WFI counseling (eight, twice monthly 50-min sessions) provided work coaching and modification, care coordination and cognitive behavioral therapy. Adjusted mixed effects models compared the WFI vs. UC group preintervention to 4-month postintervention change in at-work limitations measured by the Work Limitations Questionnaire. Secondary outcome analysis compared the change in self-reported absences and depression symptom severity (Patient Health Questionnaire PHQ-9 scores).
RESULTS: Work productivity loss scores improved 43.0% in the WFI group vs. 4.8% in UC (difference in change: P<.001). Absence days declined by 58.3% in WFI vs. 0.0% in UC (difference in change: P=.09). Mean PHQ-9 depression symptom severity declined 44.2% in WFI vs. 5.3% in UC (difference in change: P<.001).
CONCLUSION: At 4 months, the WFI was more effective than UC on two of the three outcomes. It could be an important mental and functional health improvement resource for the employed dysthymic population.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Dysthymia; Economic issues; Mood disorder; Outcome studies; Work productivity

Mesh:

Year:  2015        PMID: 25892151      PMCID: PMC4457606          DOI: 10.1016/j.genhosppsych.2015.04.001

Source DB:  PubMed          Journal:  Gen Hosp Psychiatry        ISSN: 0163-8343            Impact factor:   3.238


  53 in total

1.  Five-year course and outcome of dysthymic disorder: A prospective, naturalistic follow-up study.

Authors:  D N Klein; J E Schwartz; S Rose; J B Leader
Journal:  Am J Psychiatry       Date:  2000-06       Impact factor: 18.112

2.  A randomized clinical trial of a telephone depression intervention to reduce employee presenteeism and absenteeism.

Authors:  Debra Lerner; David A Adler; William H Rogers; Hong Chang; Annabel Greenhill; Elina Cymerman; Francisca Azocar
Journal:  Psychiatr Serv       Date:  2015-03-01       Impact factor: 3.084

3.  Assessing the performance of a new depression screener for primary care (PC-SAD).

Authors:  William H Rogers; Ira B Wilson; Kathleen M Bungay; Diane J Cynn; David A Adler
Journal:  J Clin Epidemiol       Date:  2002-02       Impact factor: 6.437

4.  The PHQ-9: validity of a brief depression severity measure.

Authors:  K Kroenke; R L Spitzer; J B Williams
Journal:  J Gen Intern Med       Date:  2001-09       Impact factor: 5.128

5.  Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire.

Authors:  R L Spitzer; K Kroenke; J B Williams
Journal:  JAMA       Date:  1999-11-10       Impact factor: 56.272

Review 6.  Antidepressant drug effects and depression severity: a patient-level meta-analysis.

Authors:  Jay C Fournier; Robert J DeRubeis; Steven D Hollon; Sona Dimidjian; Jay D Amsterdam; Richard C Shelton; Jan Fawcett
Journal:  JAMA       Date:  2010-01-06       Impact factor: 56.272

Review 7.  Selective serotonin reuptake inhibitors and tricyclic antidepressants in the acute treatment of chronic depression and dysthymia: a systematic review and meta-analysis.

Authors:  A von Wolff; L P Hölzel; A Westphal; M Härter; L Kriston
Journal:  J Affect Disord       Date:  2012-09-07       Impact factor: 4.839

Review 8.  Dysthymia in clinical practice:course, outcome and impact on the community.

Authors:  M B Keller
Journal:  Acta Psychiatr Scand Suppl       Date:  1994

9.  The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R).

Authors:  Ronald C Kessler; Patricia Berglund; Olga Demler; Robert Jin; Doreen Koretz; Kathleen R Merikangas; A John Rush; Ellen E Walters; Philip S Wang
Journal:  JAMA       Date:  2003-06-18       Impact factor: 56.272

10.  Job performance deficits due to depression.

Authors:  David A Adler; Thomas J McLaughlin; William H Rogers; Hong Chang; Leueen Lapitsky; Debra Lerner
Journal:  Am J Psychiatry       Date:  2006-09       Impact factor: 18.112

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  6 in total

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Authors:  Manish K Jha; Abu Minhajuddin; Tracy L Greer; Thomas Carmody; A John Rush; Madhukar H Trivedi
Journal:  Am J Psychiatry       Date:  2016-08-13       Impact factor: 18.112

2.  Time, Age, and Predictors of Psychosocial Outcome in Borderline Personality Disorder.

Authors:  Paul H Soloff; Laurel Chiappetta
Journal:  J Pers Disord       Date:  2018-09-04

3.  10-Year Outcome of Suicidal Behavior in Borderline Personality Disorder.

Authors:  Paul H Soloff; Laurel Chiappetta
Journal:  J Pers Disord       Date:  2018-02-22

4.  Managing Depressive Symptoms in the Workplace Using a Web-Based Self-Care Tool: A Pilot Randomized Controlled Trial.

Authors:  Abigail Hirsch; Jason Luellen; Jared M Holder; Gregory Steinberg; Teresa Dubiel; Anna Blazejowskyj; Krista Schladweiler
Journal:  JMIR Res Protoc       Date:  2017-04-04

5.  Efficacy of an indicated prevention strategy on sickness absence and termination of the employment contract: a 5-year follow-up study.

Authors:  Sophie H Klasen; Ludovic Gpm van Amelsvoort; Nicole Wh Jansen; Jos Jm Slangen; Gladys Tjin A Ton; IJmert Kant
Journal:  Scand J Work Environ Health       Date:  2021-01-07       Impact factor: 5.024

6.  Interventions to improve return to work in depressed people.

Authors:  Karen Nieuwenhuijsen; Jos H Verbeek; Angela Neumeyer-Gromen; Arco C Verhoeven; Ute Bültmann; Babs Faber
Journal:  Cochrane Database Syst Rev       Date:  2020-10-13
  6 in total

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