A Chassort1, J Coutherut2, A Moreau-Klein3, C Gras-Le Guen4, D Trewick5, F Raffi6, C Biron7. 1. Service de maladies infectieuses et tropicales, CHU de Nantes, 1, place Alexis-Ricordeau, 44093 Nantes cedex 1, France. Electronic address: arianechassort@hotmail.com. 2. Centre de vaccinations polyvalentes, CHU de Nantes, 5, rue du Pr-Yves-Boquien, 44093 Nantes cedex 1, France. Electronic address: julie.coutherut@chu-nantes.fr. 3. Laboratoire de virologie, CHU de Nantes, quai Moncousu, 44093 Nantes cedex 1, France. Electronic address: anne.moreauklein@chu-nantes.fr. 4. Service de pédiatrie, CHU de Nantes, 7, quai Moncousu, 44093 Nantes cedex 1, France. Electronic address: christele.grasleguen@chu-nantes.fr. 5. Pôle des urgences, CHU de Nantes, 9, quai Moncousu, 44093 Nantes cedex 1, France. Electronic address: david.trewick@chu-nantes.fr. 6. Service de maladies infectieuses et tropicales, CHU de Nantes, 1, place Alexis-Ricordeau, 44093 Nantes cedex 1, France. Electronic address: francois.raffi@chu-nantes.fr. 7. Service de maladies infectieuses et tropicales, CHU de Nantes, 1, place Alexis-Ricordeau, 44093 Nantes cedex 1, France; Centre de vaccinations polyvalentes, CHU de Nantes, 5, rue du Pr-Yves-Boquien, 44093 Nantes cedex 1, France. Electronic address: charlotte.biron@chu-nantes.fr.
Abstract
BACKGROUND: Many cases of measles in adults were notified during the epidemic in France in 2008. Studying these cases can lead to a better understanding of their potential complications, little data having been reported on renal dysfunction during measles. METHODS: A retrospective study of biologically confirmed measles cases in patients hospitalized for more than 24 hours was carried out in the Nantes Teaching Hospital, between January and December 2011. The renal function was assessed using the modification of diet in renal disease (MDRD) equation. RESULTS: Thirty-eight patients were included, 17 (45%) presented with a clearance below 90 mL/min. One patient presented with acute renal failure, with a clearance at 37 mL/min, and proteinuria at 2.8 g/L. His renal function was restored on day 2. CONCLUSION: Acute renal failure can occur during measles in adults. Serum creatinine should be systematically assessed during the initial medical evaluation.
BACKGROUND: Many cases of measles in adults were notified during the epidemic in France in 2008. Studying these cases can lead to a better understanding of their potential complications, little data having been reported on renal dysfunction during measles. METHODS: A retrospective study of biologically confirmed measles cases in patients hospitalized for more than 24 hours was carried out in the Nantes Teaching Hospital, between January and December 2011. The renal function was assessed using the modification of diet in renal disease (MDRD) equation. RESULTS: Thirty-eight patients were included, 17 (45%) presented with a clearance below 90 mL/min. One patient presented with acute renal failure, with a clearance at 37 mL/min, and proteinuria at 2.8 g/L. His renal function was restored on day 2. CONCLUSION:Acute renal failure can occur during measles in adults. Serum creatinine should be systematically assessed during the initial medical evaluation.
Authors: Christophe Masset; Paul Le Turnier; Céline Bressollette-Bodin; Karine Renaudin; François Raffi; Jacques Dantal Journal: Int J Mol Sci Date: 2022-10-10 Impact factor: 6.208