Literature DB >> 25891165

Recipient factors associated with having a potential living donor for liver transplantation.

Adam Doyle1, Rania N Rabie1,2, Arastoo Mokhtari1, Mark Cattral1, Anand Ghanekar1, David Grant1, Paul Greig1, Gary Levy1, Leslie Lilly1, Ian McGilvray1, Markus Selzner1, Nazia Selzner1, Eberhard L Renner1.   

Abstract

Because of a persistent discrepancy between the demand for liver transplantation (LT) and the supply of deceased donor organs, there is an interest in increasing living donation rates at centers trained in this method of transplantation. We examined a large socioeconomically heterogeneous cohort of patients listed for LT to identify recipient factors associated with living donation. We retrospectively reviewed 491 consecutive patients who were listed for LT at our center over a 24-month period. Demographic, medical, and socioeconomic data were extracted from electronic records and compared between those who had a potential living donor (LD) volunteer for assessment and those who did not; 245 patients (50%) had at least 1 potential LD volunteer for assessment. Multivariate logistic regression analysis identified that patients with a LD were more likely to have Child-Pugh C disease (odds ratio [OR], 2.44; P = 0.02), and less likely to be older (OR, 0.96; P = 0.002), single (OR, 0.34; P = 0.006), divorced (OR, 0.53; P = 0.03), immigrants (OR, 0.38; P = 0.049), or from the lowest income quintile (OR, 0.44; P = 0.02). In conclusion, this analysis has identified several factors associated with access to living donation. More research is warranted to define and overcome barriers to living donor liver transplantation through targeted interventions in underrepresented populations.
© 2015 American Association for the Study of Liver Diseases.

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Year:  2015        PMID: 25891165     DOI: 10.1002/lt.24148

Source DB:  PubMed          Journal:  Liver Transpl        ISSN: 1527-6465            Impact factor:   5.799


  4 in total

1.  Barriers to access in pediatric living-donor liver transplantation.

Authors:  Douglas B Mogul; Joy Lee; Tanjala S Purnell; Allan B Massie; Tanveen Ishaque; Dorry L Segev; John F P Bridges
Journal:  Pediatr Transplant       Date:  2019-06-19

2.  Demographic and Urbanization Disparities of Liver Transplantation in Taiwan.

Authors:  Pei-Hung Wen; Chin-Li Lu; Carol Strong; Yih-Jyh Lin; Yao-Li Chen; Chung-Yi Li; Chiang-Chin Tsai
Journal:  Int J Environ Res Public Health       Date:  2018-01-23       Impact factor: 3.390

3.  Individual and neighborhood socioeconomic status in the prediction of liver transplantation among patients with liver disease: A population-based cohort study in Taiwan.

Authors:  Chi-Chu Liu; Chin-Li Lu; Hari Basuki Notobroto; Chiang-Chin Tsai; Pei-Hung Wen; Chung-Yi Li
Journal:  Medicine (Baltimore)       Date:  2019-03       Impact factor: 1.817

Review 4.  A scoping review of inequities in access to organ transplant in the United States.

Authors:  Christine Park; Mandisa-Maia Jones; Samantha Kaplan; Felicitas L Koller; Julius M Wilder; L Ebony Boulware; Lisa M McElroy
Journal:  Int J Equity Health       Date:  2022-02-12
  4 in total

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