Literature DB >> 2589050

Protection against cataract by aspirin, paracetamol and ibuprofen.

J J Harding1, M Egerton, R S Harding.   

Abstract

Results of a case-control of 423 cataract patients and 608 controls in Oxfordshire shows that the protective effect against cataract associated with consumption of aspirin-like analgesics (aspirin, paracetamol and ibuprofen family) is manifest even at low doses. Less than 150 g total dose was associated with a halving of the risk of cataract extraction.

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Year:  1989        PMID: 2589050     DOI: 10.1111/j.1755-3768.1989.tb04102.x

Source DB:  PubMed          Journal:  Acta Ophthalmol (Copenh)        ISSN: 0001-639X


  12 in total

Review 1.  Prevention strategies for age related cataract: present limitations and future possibilities.

Authors:  N G Congdon
Journal:  Br J Ophthalmol       Date:  2001-05       Impact factor: 4.638

Review 2.  Zeta-crystallin: a moonlighting player in cancer.

Authors:  Matteo Lulli; Daniele Nencioni; Laura Papucci; Nicola Schiavone
Journal:  Cell Mol Life Sci       Date:  2019-09-28       Impact factor: 9.261

Review 3.  Aspirin and the elderly. Current status.

Authors:  C Silagy
Journal:  Drugs Aging       Date:  1993 Jul-Aug       Impact factor: 3.923

4.  Changes of the thiol levels in the corneas of the diabetic rats: effect of carnosine, aspirin and a combination eye drops.

Authors:  Qiong Shi; Hong Yan
Journal:  Int J Ophthalmol       Date:  2010-09-18       Impact factor: 1.779

Review 5.  Can drugs or micronutrients prevent cataract?

Authors:  J J Harding
Journal:  Drugs Aging       Date:  2001       Impact factor: 3.923

6.  Aspirin inhibits TGFβ2-induced epithelial to mesenchymal transition of lens epithelial cells: selective acetylation of K56 and K122 in histone H3.

Authors:  Mi-Hyun Nam; Andrew J O Smith; Mina B Pantcheva; Ko Uoon Park; Joseph A Brzezinski; James J Galligan; Kristofer Fritz; I Michael Wormstone; Ram H Nagaraj
Journal:  Biochem J       Date:  2020-01-17       Impact factor: 3.857

7.  Glutathione adducts, not carbamylated lysines, are the major modification of lens alpha-crystallins from renal failure patients.

Authors:  J B Smith; G A Shun-Shin; Y Sun; L R Miesbauer; Z Yang; Z Yang; X Zhou; J Schwedler; D L Smith
Journal:  J Protein Chem       Date:  1995-04

8.  In vivo acetylation identified at lysine 70 of human lens alphaA-crystallin.

Authors:  P P Lin; R C Barry; D L Smith; J B Smith
Journal:  Protein Sci       Date:  1998-06       Impact factor: 6.725

Review 9.  Pharmacological treatment strategies in age-related cataracts.

Authors:  J J Harding
Journal:  Drugs Aging       Date:  1992 Jul-Aug       Impact factor: 3.923

10.  Glycation (non-enzymic glycosylation) inactivates glutathione reductase.

Authors:  R Blakytny; J J Harding
Journal:  Biochem J       Date:  1992-11-15       Impact factor: 3.857

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