Literature DB >> 2589023

Establishment of a human glioma cell line bearing a homogeneously staining chromosomal region and releasing alpha- and beta-type transforming growth factors.

H Kanno1, T Kuwabara, M Shinonaga, C C Chang, Y Tanaka, Y Sugio, H Morita, H Yasumitsu, M Umeda, Y Nagashima.   

Abstract

A human glioma cell line (YKG1), which was positively identified for glial fibrillary acidic (GFA) and S-100 proteins, was established from a surgical specimen of a patient with glioblastoma. Chromosome analysis of the cells revealed a homogeneously staining region (HSR) on a marker chromosome. The assay for transforming growth factors (TGFs) in the conditioned medium of the cell line revealed that it contained high levels of alpha- and beta-type TGFs, which might regulate the growth of glioblastoma and influence on the peritumoral tissues.

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Year:  1989        PMID： 2589023     DOI： 10.1007/bf00308954

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN： 0001-6322            Impact factor:   17.088


  36 in total

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Journal:  Science       Date:  1968-07-26       Impact factor: 47.728

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Authors:  J Pontén; B Westermark
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Authors:  H Kanno; T Kuwabara; H Yasumitsu; M Umeda
Journal:  J Neurosurg       Date:  1988-05       Impact factor: 5.115

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Journal:  J Neuropathol Exp Neurol       Date:  1981-05       Impact factor: 3.685
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  4 in total

Review 1.  Angiogenic growth factors in neural embryogenesis and neoplasia.

Authors:  D Zagzag
Journal:  Am J Pathol       Date:  1995-02       Impact factor: 4.307

2.  Effect of endothelin-1 as growth factor on a human glioma cell line; its characteristic promotion of DNA synthesis.

Authors:  T Asano; M Aoyagi; K Hirakawa; Y Ikawa
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130

3.  Immunolocalization of alpha-transforming growth factor in the developing rat mammary gland in vivo, rat mammary cells in vitro and in human breast diseases.

Authors:  J McAndrew; P S Rudland; A M Platt-Higgins; J A Smith
Journal:  Histochem J       Date:  1994-04

4.  Hyperthermia and chemotherapy using Fe(Salen) nanoparticles might impact glioblastoma treatment.

Authors:  Makoto Ohtake; Masanari Umemura; Itaru Sato; Taisuke Akimoto; Kayoko Oda; Akane Nagasako; Jeong-Hwan Kim; Takayuki Fujita; Utako Yokoyama; Tomohiro Nakayama; Yujiro Hoshino; Mai Ishiba; Susumu Tokura; Masakazu Hara; Tomoya Muramoto; Sotoshi Yamada; Takatsugu Masuda; Ichio Aoki; Yasushi Takemura; Hidetoshi Murata; Haruki Eguchi; Nobutaka Kawahara; Yoshihiro Ishikawa
Journal:  Sci Rep       Date:  2017-02-20       Impact factor: 4.379
  4 in total

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